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STUDY 2006 PDF file 162Kb
Long-acting depot naltrexone extends opiate abstinence

A long-acting version of the opiate blocking drug naltrexone nearly doubled the time heroin dependent patients were retained in abstinence-based treatment, creating an opiate-free space during which to begin the construction of non-addicted lifestyles.

STUDY 2006 PDF file 170Kb
Naltrexone aids primary care alcohol treatment

Findings from the large-scale US COMBINE study add to accumulating evidence that the drug naltrexone is a valuable therapeutic enhancement for the kind of dependent drinkers and the kind of treatments suited to primary care settings.

STUDY 2006 PDF file 198Kb
Drink-driving cut by 30-minute talk with hospital patients

Patients admitted to a US hospital following a traffic accident had fewer arrests for drink-driving after a short talk with hospital staff about their drinking, the first such finding and one which reinforced the case for hospital-based brief interventions.

STUDY 2006 PDF file 279Kb
British study makes a case for buprenorphine as first line heroin detox option

Compared to a standard lofexidine regime, buprenorphine was preferred by opiate dependent patients and enabled more to complete outpatient detoxification.

STUDY 2010 HTM file
Counselor motivational interviewing skills and young adult change talk articulation during brief motivational interventions

In the study of Swiss army conscripts, reflective listening emerged as possibly the key active ingredient in a brief alcohol intervention based on motivational interviewing.

REVIEW 2009 HTM file
Pharmacotherapies for the treatment of opioid dependence: efficacy, cost-effectiveness and implementation guidelines

From some of the same Australian authors who produced classic texts on maintenance prescribing for heroin addiction, a major new text analysing research on all types of drug-based interventions including maintenance, opiate-blocking drugs, and managing withdrawal.

STUDY 2010 HTM file
Twelve-month follow-up results from a randomized controlled trial of a brief personalized feedback intervention for problem drinkers

With other similar work, this Canadian study suggests that internet-based programs which offer feedback to the user on their drinking in relation to the population and on the risks they may be running can lead to drinking reductions of the same order as face-to-face advice.

STUDY 2010 HTM file
Review of treatment for cocaine dependence

This comprehensive review found strong evidence that some drugs can help treat cocaine dependence and that cognitive-behavioural therapy is a powerful tool to manage cravings and stresses, especially when allied with effective pharmacotherapies.

REVIEW ABSTRACT 2009 HTM file
Cognitive-behavioral treatment with adult alcohol and illicit drug users: a meta-analysis of randomized controlled trials

Cognitive-behavioural therapies are among the most widespread and influential approaches to substance use, yet this analysis found they conferred just a small advantage over other therapies. Perhaps other features are more important than the therapeutic 'brand'.

STUDY 2009 HTM file
Secondary prevention of hazardous alcohol consumption in psychiatric out-patients: a randomised controlled study

Set in Sweden, the first study among psychiatric outpatients to test brief alcohol interventions against screening alone found worthwhile extra drinking reductions after brief motivational advice. Use of a telephone-based intervention was another innovation.


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