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STUDY 2001 PDF file 197Kb
Alcohol dependence typology may help decide which drugs to prescribe
In two US studies drugs with an opposing impact on a key neurotransmitter system helped different types of alcoholics curb their drinking, raising the prospect of being able to match patients to the drug elements of their treatments.
STUDY 2001 PDF file 274Kb
Antabuse reduces cocaine and alcohol use among opiate maintenance patients
Regular alcohol and cocaine use are common among opiate dependent patients and only partially (if at all) affected by opioid maintenance treatment; US studies suggest that disulfiram can curb use of both these drugs among maintenance patients.
OFFCUT 2001 PDF file 183Kb
US report on drug treatments for alcoholism builds into a personalised, abstracted bibliography
Now a little dated, the US government report Pharmacotherapy for alcohol dependence on drug treatments for Alcoholism is still hard to beat for authority and comprehensiveness.
REVIEW 2002 PDF file 174Kb
Convincing evidence that acamprosate and naltrexone help prevent alcohol relapse
Despite patchy results in individual studies, two meta-analyses which combined findings from rigorous trials have confirmed that acamprosate and naltrexone help prevent relapse after detoxification from alcohol. See extended text for further studies.
STUDY 2002 PDF file 199Kb
A way to encourage drinkers to stick with naltrexone treatment
An intervention which helps overcome the major impediments to naltrexone treatment of alcoholism – patients don't take the pills or drop out – has now been codified in a book which acts as a manual for conducting the intervention.
STUDY 2003 PDF file 188Kb
Naltrexone helps heavy drinkers gain control
In Spain naltrexone helped young regular binge drinkers cut back, potentially extending its role from alcoholics seeking treatment at specialist clinics to problem drinkers identified in other settings such as primary care.
STUDY 2004 PDF file 105Kb
Alcohol patients on acamprosate do well just seeing the doctor
Trials of the drug acamprosate in the treatment of alcohol dependence have almost invariably paired it with psychosocial therapies, but two European studies suggest patients do just as well in normal medical care.
STUDY 2005 PDF file 142Kb
Anti-alcohol drug also reduces cocaine use
US trial shows that when cocaine dependence and heavy drinking are intertwined, prescribing the anti-alcohol medication disulfiram helps resolve both problems, unless patients are so wedded to drink that they stop taking the pills.
STUDY 2005 PDF file 170Kb
'Real-world' studies show that medications do suppress heavy drinking
Three trials found that drugs commonly used to treat alcohol dependence improve outcomes for an appreciable minority of patients, even under conditions close to normal practice. Together they offer clues to who benefits most from each medication.
STUDY 2005 PDF file 112Kb
Pharmacotherapies which work with men do not help women
Emerging indications from studies of disulfiram treatment of cocaine dependence and sertraline for alcohol dependence that pharmacotherapies which work for men do not always help women.
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