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You have found 82 document(s) after clicking the search option in a hot topic entry. Starting with the most recently added or updated of our analyses, the list shows in orange whether the original document was a study, review or some other type of document, year it was published, the type of file you will download when you click the title, and for PDFs its size. In blue is the document’s title; click to download. Below is a brief description. Remember we only list documents relevant to the effectiveness of drug or alcohol interventions in the United Kingdom.

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STUDY 2016 HTM file
Extended-release naltrexone to prevent opioid relapse in criminal justice offenders

Added to basic counselling alone, monthly injections of the opioid-blocking drug naltrexone helped prevent relapse among US offenders with a history of opioid dependence recently released from prison or under criminal justice supervision in the community – findings most applicable to those who prefer opioid-free to opioid-maintenance treatments.

STUDY 2014 HTM file
Methadone induction in primary care for opioid dependence: a pragmatic randomized trial (ANRS Methaville)

From France the first study to randomly allocate patients to start methadone maintenance either in primary care or at a specialist centre found primary care more attractive to patients, and no less effective at reducing street-opioid use and promoting engagement and retention.

STUDY 2018 HTM file
A randomized, open label trial of methadone continuation versus forced withdrawal in a combined US prison and jail: findings at 12 months post-release

From the USA, a rare randomised trial found in favour of continuing methadone maintenance when patients entered prison rather than compulsory withdrawal. The potential benefits were most apparent in the near-100% continuation of protective treatment during the highly overdose-prone weeks after leaving prison.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell E1: Local and national systems; Reducing harm

Seminal and key studies relating to local, regional and national systems for effectively and cost-effectively reducing harm.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell D1: Organisational functioning; Reducing harm

Seminal and key studies on the influence of the organisation on reducing drug-related harm.

MATRIX CELL 2017 HTM file
Drug Matrix cell C1: Management/supervision: Reducing harm

Seminal and key studies on the role of management and supervision in reducing harm associated with illegal drug use.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell B1: Practitioners; Reducing harm

Seminal and key studies on the impact of the practitioner on harm reduction. Trust emerges as a fundamental ingredient to harm reduction work with users of illegal drugs. Reconceptualise needle exchanges as safe havens in a largely rejecting world, and explore why a Philadelphia methadone counsellor stood out – for the wrong reasons.

MATRIX CELL 2017 HTM file
Drug Matrix cell A1: Interventions; Reducing harm

Seminal and key studies on the effectiveness of harm reduction interventions such as needle exchanges.

DOCUMENT 2017 HTM file
Drug misuse and dependence: UK guidelines on clinical management

Last published in 2007, there is no more important document for UK clinicians involved in treating problem drug use than the so-called ‘Orange guidelines’. This major update offers detailed guidance on the range of problems, settings and patients clinicians encounter, substantially informing judgements of what constitutes good medical practice.

DOCUMENT 2016 HTM file
Harm reduction database Wales: take home naloxone 2015–16

Report charting the roll-out of ‘take-home naloxone’ in Wales up to 2016, a harm-reduction measure implemented to prevent deaths involving opiate-type drugs.


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