Drugs: the complete collection

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Drugs: the complete collection

All Effectiveness Bank analyses to date of documents related to use and problem use of illegal drugs starting with the analyses most recently added or updated, totalling today 809 documents.

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STUDY 2019 HTM file
Do electronic health record prompts increase take-home naloxone administration for emergency department patients after an opioid overdose?

Marino R., Landau A., Lynch M. et al.
Addiction: 2019, 114, p. 1575–1581.
[Consultation draft subject to amendment and correction.] Emergency department physicians regularly treat people who have had an opioid overdose, but may not be making the most of the opportunity to provide take-home naloxone. Study tests the effectiveness of a prompt in the patients’ electronic health records for boosting physician prescribing of this ‘overdose antidote’.

STUDY 2018 HTM file
Usage of low dead space syringes and association with hepatitis C prevalence amongst people who inject drugs in the UK

Trickey A., May M.T., Hope V. et al.
Drug and Alcohol Dependence: 2018, 192, p. 118–124.
For people who share injecting equipment, ‘low dead space’ syringes may lead to a reduced risk of becoming infected with blood-borne viruses by limiting the volume of fluid that is drawn up but not injected. However, they may not (yet) be suitable for all types of injectors or injections.

REVIEW 2019 HTM file
A meta-analysis of the efficacy of case management for substance use disorders: a recovery perspective

Vanderplasschen W., Rapp R.C., De Maeyer J. et al.
Frontiers in Psychiatry: 2019, 10(186).
How does an intervention designed to enhance coordination and continuity of services, known as ‘case management’, compare to treatment as usual? Is there any evidence to suggest that it can directly or indirectly improve recovery outcomes?

HOT TOPIC 2020 HTM file
The complexity and challenge of ‘dual diagnosis’

Ashton M., Davies N.
One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. Whether to focus on mental health problems or substance use problem when the patient exhibits both is long-standing conundrum which still puzzles today’s treatment services. Arising with as many as three-quarters of the drug treatment caseload, deciding how to respond is a is a major issue.

STUDY 2020 HTM file
Comparative effectiveness of different treatment pathways for opioid use disorder

Wakeman S.E., Larochelle M.R., Ameli O. et al.
JAMA Network Open, 2020, 3(2), e1920622.
How do different pathways for the treatment of problem opioid use compare under real-world conditions? For US patients with health insurance, opioid substitution therapy was associated with the greatest risk reduction. However, its protective effect may not be fully realised while federal and insurance plan restrictions continue to limit access to this treatment option.

STUDY 2019 HTM file
Modelling the combined impact of interventions in averting deaths during a synthetic-opioid overdose epidemic

Irvine M.A., Kuo M., Buxton J.A. et al.
Addiction: 2019, 114, p. 1602–1613.
In the Canadian province of British Columbia there was a rapid rise in overdose deaths from 2015, leading to the declaration of a public health emergency in 2016. The response rested on three key interventions: take-home naloxone, opioid substitution therapy, and drug consumption rooms. The province’s highly detailed surveillance data offered an opportunity to estimate their collective and individual impacts on opioid overdose deaths.

STUDY 2012 HTM file
Housing first for severely mentally ill homeless methadone patients

Appel P.W., Tsemberis S., Joseph H. et al.
Journal of Addictive Diseases: 2012, 31, p. 270–277.
Homelessness is a significant obstacle to regular participation in methadone maintenance treatment, particularly among people leaving prison. This study in a major US city examines whether a ‘housing first’ programme could improve outcomes among this cohort.

DOCUMENT 2019 HTM file
Canadian guidelines on opioid use disorder among older adults

Canadian Coalition for Seniors’ Mental Health
Canadian Coalition for Seniors’ Mental Health, 2019
What Canadian experts judged to be the best clinical practice around the prevention, assessment, and treatment of opioid use disorders in older people.

DOCUMENT 2019 HTM file
Canadian guidelines on cannabis use disorder among older adults

Canadian Coalition for Seniors’ Mental Health
Canadian Coalition for Seniors’ Mental Health, 2019
What Canadian experts judged to be the best clinical practice around the prevention, assessment, and treatment of cannabis use disorders in older people.

STUDY 2015 HTM file
The impact of paying treatment providers for outcomes: difference-in-differences analysis of the ‘payment by results for drugs recovery’ pilot

Mason T., Sutton M., Whittaker W. et al
Addiction: 2015, 110(7), p. 1120–1128.
A flagship drug treatment policy initiative appears to have backfired in England, where the government’s pilot payment-by-results schemes seem to have led to fewer successful completions of treatment and more prospective patients declining treatment.


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