Drugs: the complete collection
 Drugs: the complete collection

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Drugs: the complete collection

All Effectiveness Bank analyses to date of documents related to use and problem use of illegal drugs starting with the analyses most recently added or updated, totalling today 815 documents.

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STUDY 2020 HTM file
Improving access to care for people who inject drugs: qualitative evaluation of Project ITTREAT – an integrated community hepatitis C service

Phillips C., Schulkind J., O’Sullivan M. et al.
Journal of Viral Hepatitis: 2020, 27, p. 176–187.
A UK-based project placed a dedicated full-time hepatitis C nurse into a drug and alcohol treatment service. The experiences of people who inject drugs and attended the service reveal the degree to which this strategy can remove barriers to the infection treatment so crucial to containing the virus.

MATRIX CELL 2020 HTM file
Drug Treatment Matrix cell C4: Management/supervision; Psychosocial therapies

Ashton M.
Seminal and key studies on management and supervision in psychosocial therapies. Findings challenge managers to invest in the post-training ‘coaching’ needed to make a difference for patients, and to set up systems alerting therapists to how well their clients are doing – especially when they are doing badly.

STUDY 2019 HTM file
Criminal justice outcomes over 5 years after randomization to buprenorphine-naloxone or methadone treatment for opioid use disorder

Evans E.A., Zhu Y., Yoo C. et al.
Addiction: 2019, 114, p. 1396–1404.
Can a limited period of being prescribed opiate-type medications generate longer term reductions in the criminal behaviour of patients dependent on illegal opiates like heroin? And of the two main medications – buprenorphine and methadone – which performs best? It seems a key factor is how well they retain patients in treatment.

STUDY 2019 HTM file
Do electronic health record prompts increase take-home naloxone administration for emergency department patients after an opioid overdose?

Marino R., Landau A., Lynch M. et al.
Addiction: 2019, 114, p. 1575–1581.
Emergency department physicians regularly treat people who have had an opioid overdose, but they may not be making the most of the opportunity to provide take-home naloxone. Can a prompt in the patients’ electronic health records boost prescribing of this lifesaving ‘overdose antidote’?

MATRIX CELL 2020 HTM file
Drug Treatment Matrix cell E3: Treatment systems; Medical treatment

Ashton M.
Seminal and key studies relating to local, regional and national systems for effectively and cost-effectively providing medical interventions and treatment in medical settings. Highlights a simple innovation which transformed detoxification recyclers into typical patients, asks if you agree with an expert group’s vision of what a good quality service looks like, and questions whether Britain is making progress on organising care for mentally ill problem drug users.

HOT TOPIC 2020 HTM file
Time for safer injecting spaces in Britain?

Davies N.
‘Hot topics’ offer background and analysis on important issues which sometimes generate heated debate. Drug consumption rooms are a particularly contentious form of harm reduction, viewed on one hand as a practical, humane, life-saving approach to dangerous drug use, and on the other, as an endorsement of drugtaking and a dereliction of the duty to treat people dependent on drugs.

STUDY 2018 HTM file
Usage of low dead space syringes and association with hepatitis C prevalence amongst people who inject drugs in the UK

Trickey A., May M.T., Hope V. et al.
Drug and Alcohol Dependence: 2018, 192, p. 118–124.
For people who share injecting equipment, ‘low dead space’ syringes may lead to a reduced risk of becoming infected with blood-borne viruses by limiting the volume of fluid that is drawn up but not injected. However, they may not (yet) be suitable for all types of injectors or injections.

REVIEW 2019 HTM file
A meta-analysis of the efficacy of case management for substance use disorders: a recovery perspective

Vanderplasschen W., Rapp R.C., De Maeyer J. et al.
Frontiers in Psychiatry: 2019, 10(186).
How does an intervention designed to enhance coordination and continuity of services, known as ‘case management’, compare to treatment as usual? Is there any evidence to suggest that it can directly or indirectly improve recovery outcomes?

HOT TOPIC 2020 HTM file
The complexity and challenge of ‘dual diagnosis’

Ashton M., Davies N.
One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. Whether to focus on mental health problems or substance use problem when the patient exhibits both is long-standing conundrum which still puzzles today’s treatment services. Arising with as many as three-quarters of the drug treatment caseload, deciding how to respond is a is a major issue.

STUDY 2020 HTM file
Comparative effectiveness of different treatment pathways for opioid use disorder

Wakeman S.E., Larochelle M.R., Ameli O. et al.
JAMA Network Open, 2020, 3(2), e1920622.
How do different pathways for the treatment of problem opioid use compare under real-world conditions? For US patients with health insurance, opioid substitution therapy was associated with the greatest risk reduction. However, its protective effect may not be fully realised while federal and insurance plan restrictions continue to limit access to this treatment option.


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