Drugs: the complete collection
 Drugs: the complete collection

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Drugs: the complete collection

All Effectiveness Bank analyses to date of documents related to use and problem use of illegal drugs starting with the analyses most recently added or updated, totalling today 783 documents.

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STUDY 2010 HTM file
Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK

Cornish R., Macleod J., Strang J. et al.
British Medical Journal: 2010, 341:c5475.
This British study concluded that it takes extended opiate substitute prescribing to realise the treatment's life-saving potential. The implication is that the current push to get people off methadone sooner could cost lives.

STUDY 2008 HTM file
Final report on the evaluation of ‘Option 2’

Forrester D., Pokhrel S., McDonald L. et al.
Welsh Assembly Government, 2008.
This evaluation of an intensive child protection service for children with substance misusing parents was the first in Britain to recruit an adequate comparison sample, a vital step in assessing effectiveness. Main finding was reduced need for long-term removal from the home.

DOCUMENT 2012 HTM file
Practice standards for young people with substance misuse problems

Gilvarry E., McArdle P., O’Herlihy A. et al, eds.
[UK] Royal College of Psychiatrists, 2012.
Practice standards developed by the UK’s Royal College of Psychiatrists on working with young people aged 18 or under with substance misuse problems, intended (if followed) to promote high quality screening, assessment and treatment for these young people.

REVIEW 2012 HTM file
BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP

Lingford-Hughes A.R., Welch S., Peters L. et al.
Journal of Psychopharmacology: 2012, 26(7), p. 899–952.
Practitioner-friendly review from the British Association for Psychopharmacology on drug-based treatments for substance dependence offer authoritative, evidence-based guidance to prescribers and others; they also demonstrate the limitations of trying to cure over-use of drugs with drugs.

STUDY 2013 HTM file
Medically assisted recovery from opiate dependence within the context of the UK drug strategy: methadone and suboxone (buprenorphine-naloxone) patients compared

McKeganey N., Russell C, Cockayne L.
Journal of Substance Abuse Treatment: 2013, 44(1), p. 97–102.
Opiate dependent patients in Scotland who opted for or were allocated to methadone sustained their abstinence from heroin as well as those on buprenorphine, but buprenorphine was far better at helping continuing heroin users cut back – suggestive, but the study’s constraints make the practice implications unclear.

REVIEW 2012 HTM file
Meta-analyses of seven of the National Institute on Drug Abuse’s principles of drug addiction treatment

Pearson F.S., Prendergast M.L., Podus D. et al.
Journal of Substance Abuse Treatment: 2012, 43, p. 1–11.
In this massive enterprise, analysts dissected 232 treatment-comparison studies to test the validity of the US government’s principles of effective treatment for problems related to illegal drug use. Principles relating to individualising treatment were consistently supported by the North American evidence.

REVIEW 2012 HTM file
The effects of family therapies for adolescent delinquency and substance abuse: a meta-analysis

Baldwin S.A., Christian S., Berkeljon A. et al.
Journal of Marital and Family Therapy: 2012, 38(1), p. 281–304.
Review assesses the effectiveness selling points of four largely ‘privatised’ brand-name family therapies for troubled and delinquent teens. Yes, they work better than usual or individualised approaches, but not much and not always, and most of the research has been done by people who stand to gain from positive findings.

STUDY 2010 HTM file
Vietnam veterans three years after Vietnam: how our study changed our view of heroin

Robins L.N., Helzer J.E., Hesselbrock M. et al.
American Journal on Addictions: 2010, 19, p. 203–211.
Reprint of a 1977 presentation of one of the most influential studies of heroin addiction ever conducted, which called in to question its supposed addictive qualities, the need for prolonged treatment and abstinence to overcome addiction, and whether heroin use inevitably causes major social problems.

REVIEW 2010 HTM file
Optimal provision of needle and syringe programmes for injecting drug users: a systematic review

Jones L., Pickering L., Sumnall H. et al.
International Journal of Drug Policy: 2010, 21, p. 335–342.
This thorough review formed the evidential basis for recent guidance from England's National Institute for Health and Clinical Excellence on how best to distribute sterile syringes. Maximising the proportion of injections done with sterile equipment is the key objective.

DOCUMENT 2014 HTM file
Needle and syringe programmes

National Institute for Health and Clinical Excellence.
National Institute for Health and Clinical Excellence, 2014.
The UK’s health advisory body recommends high coverage and if need be, 24-hour needle exchange to combat HIV and the hepatitis C epidemic. The aim they say is for every injector to have even more sterile injecting equipment than they need for every single injection.


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