Drugs: the complete collection
 Drugs: the complete collection

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Drugs: the complete collection

All Effectiveness Bank analyses to date of documents related to use and problem use of illegal drugs starting with the analyses most recently added or updated, totalling today 815 documents.

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DOCUMENT 2012 HTM file
Medications in recovery: re-orientating drug dependence treatment

Strang J. et al.
[UK] National Treatment Agency for Substance Misuse, 2012.
On behalf of the UK government an expert group has developed and documented a clinical consensus on how prescribing-based treatment for heroin addiction can be made more recovery-oriented in line with national strategy. Their report will be the main reference point in tussles over what recovery means for methadone services and patients.

STUDY 2013 HTM file
Drug treatment in England 2012–13

Public Health England.
Public Health England, 2013.
Agency responsible for addiction treatment in England argues that efforts to put recovery at its heart are paying off in the form of patients successfully completing treatment and not having to return, but warns that the older caseload is getting harder to move on. One concern: is treatment being de-individualised to generate a 'good news' story?

REVIEW 2010 HTM file
Psychosocial interventions for reducing injection and sexual risk behaviour for preventing HIV in drug users

Meader N., Li R., Des Jarlais D.C., et al.
Cochrane Database of Systematic Reviews: 2010, 1, art. no. CD007192.
This systematic review of 35 trials found that several sessions of information and skills training were no more effective than minimal educational interventions at reducing the kind of substance use and sexual behaviour which risks HIV infection in drug users who inject and/or use cocaine.

REVIEW 2012 HTM file
Behavioural interventions for preventing hepatitis C infection in people who inject drugs: a global systematic review

Sacks-Davis R., Horyniak D., Grebely J. et al
International Journal of Drug Policy: 2012, 23, p.176–184.
A review reporting on the results of six trials from the UK, USA and Australia finds that – at least on their own – interventions such as counselling and peer-educator training have not prevented injecting drug users becoming infected with hepatitis C.

STUDY 2009 HTM file
Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees

Brodie J.D., Case B.G., Figueroa E. et al.
American Journal of Psychiatry: 2009, 166(11), p. 1269–1277.
Severely cocaine-dependent Mexican parolees were the test bed for an epilepsy medication known after long-term use to damage vision in a substantial proportion of patients. It seemed to help at least interrupt cocaine use and also cut drinking, but are the risks worth it?

STUDY 2011 HTM file
A randomized trial of clozapine versus other antipsychotics for cannabis use disorder in patients with schizophrenia

Brunette M.F., Dawson R., O'Keefe C.D. et al.
Journal of Dual Diagnosis: 2011, 7 (1–2), p. 50–63.
Heavy cannabis use is particularly troubling in patients already struggling with schizophrenia. This study provides the first evidence from a randomised controlled trial that switching such patients to the antipsychotic clozapine may help reduce their cannabis use, but is this worth the extra risk of clozapine compared to the alternatives?

DOCUMENT 2013 HTM file
Rewarding virtue

Ashton M.
Druglink: November/December 2013.
Can we dispense with counselling, therapy, treatment as we know it, and just punish or deprive patients of rewards when they use substances in undesired ways, and reward them when they behave as we/they would wish? British services are trialling an approach about which many clinicians express major ethical concerns – contingency management.

REVIEW 2013 HTM file
Quitting drugs: quantitative and qualitative features

Heyman G.M.
Annual Review of Clinical Psychology: 2013, 9, p. 29–59.
Innovative re-analysis of US national surveys reveals that no matter how long ago someone became dependent on an illegal drug or alcohol, their chances of achieving remission remain the same. The findings challenge models which assume that progressive neural, lifestyle or psychological changes increasingly lock someone in to addiction.

STUDY 2010 HTM file
Unobserved versus observed office buprenorphine/naloxone induction: a pilot randomized clinical trial

Gunderson E.W., Wang X-Q, Fiellin D.A. et al.
Addictive Behaviors: 2010, 35(5), p. 537–540.
Having for several hours to medically monitor opiate-addicted patients starting buprenorphine maintenance is a major impediment to spreading the benefits of the treatment, but this first randomised trial suggests that many patients can manage the process safely at home.

STUDY 2011 HTM file
Probability and predictors of remission from life-time nicotine, alcohol, cannabis or cocaine dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions

Lopez-Quintero C., Hasin D.S., Pérez de los Cobos J. et al.
Addiction: 2011, 106(3), p. 657–669.
The largest recent US national survey of drink and drug problems shows that outside the addiction treatment clinic, remission is the norm and recovery common. After 14 years half the people at some time dependent on alcohol were in remission, a milestone reached for cannabis after six years, and for cocaine after just five.

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