Drugs: the complete collection
 Drugs: the complete collection

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Drugs: the complete collection

All Effectiveness Bank analyses to date of documents related to use and problem use of illegal drugs starting with the analyses most recently added or updated, totalling today 815 documents.

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STUDY 2011 HTM file
Reduction in overdose mortality after the opening of North America's first medically supervised safer injecting facility: a retrospective population-based study

Marshall B.D.L., Milloy M-J., Wood EB. et al.
Lancet: 2011, 377(9775), p. 1429–1437.
The safer injecting facility in Vancouver prevented overdose deaths but only in areas nearest the service, suggesting that often several facilities will be needed to make a city-wide impact.

STUDY 2010 HTM file
Long-term outcomes of office-based buprenorphine/naloxone maintenance therapy

Parran T.V., Adelman C.A., Merkin B. et al.
Drug and Alcohol Dependence: 2010, 106(1), p. 56–60.
Abstinence and recovery characterised by employment are priority UK policy objectives to which the extension of mutual aid is considered a major route. This US study illustrates that both the route and the objectives are not just compatible with, but may be promoted by opiate maintenance prescribing.

STUDY 2011 HTM file
Fidelity to motivational interviewing and subsequent cannabis cessation among adolescents

McCambridge J., Day M., Thomas B.A. et al.
Addictive Behaviors: 2011, 36, p. 749–754.
Offering valuable clues to how best to do motivational interviewing, this London study of cannabis-using students found they were most likely to stop using after brief interventions which embodied the spirit of the approach and featured responses from the counsellor reflecting back and elaborating on the student's comments.

STUDY 2011 HTM file
Cluster randomised trial of the effectiveness of motivational interviewing for universal prevention

McCambridge J., Hunt C., Jenkins R.J. et al.
Drug and Alcohol Dependence: 2011, 114, p. 177–184.
Compared to basic drug education, it should at least have moderated current use, but this attempt to deploy motivational interviewing as an across-the-board prevention strategy among college students in London neither did that, nor did it prevent non-users starting to use, negative findings which raise interesting questions.

STUDY 2010 HTM file
Brief counseling for reducing sexual risk and bacterial STIs among drug users. Results from project RESPECT

Semaan S., Neumann M.S., Hutchins K. et al.
Drug and Alcohol Dependence: 2010, 106, p. 7–15.
Across this large US study, injectors responded to sexual risk-reduction counselling as well as non-injectors; the evidence was there a year later in fewer infections. But why was what should have been the strongest intervention actually the weakest among this group, yet not among non-injectors?

STUDY 2011 HTM file
Translating addictions research into evidence-based practice: The Polaris CD outcomes management system

Toche-Manley L., Grissom G., Dietzen L. et al.
Addictive Behaviors: 2011, 36, p. 601–607.
Experience in California of developing and implementing a system for assessing patients' needs and matching to appropriate services offers an unusually fully developed model for promoting recovery and judging the outcomes achieved by a service in the light of its patient profile.

REVIEW 2011 HTM file
Oral naltrexone maintenance treatment for opioid dependence

Minozzi S., Amato L., Vecchi S. et al.
Cochrane Database of Systematic Reviews: 2011, 2, Art. No.: CD001333.
Authoritative synthesis of research confirms that the general run of opiate-addicted patients do almost as well given no active medication as when prescribed the opiate-blocking drug naltrexone, though it does have limited role among highly motivated and/or monitored patients with much to lose from relapsing.

STUDY 2011 HTM file
Shared decision-making: increases autonomy in substance-dependent patients

Joosten E.A.G., De Jong C.A.J., de Weert-van Oene G.H. et al.
Substance Use and Misuse: 2011, 46(8), p. 1037–1038
An innovative Dutch study tested a way of involving substance users as equals in decisions over issues addressed in their treatment. The effect was to give these typically submissive personalities a greater sense of control over their lives. Just as influential was the lead offered by the clinician's personality.

REVIEW 2010 HTM file
Cost-effectiveness of family-based substance abuse treatment

Morgan T.B., Crane D.R.
Journal of Marital and Family Therapy: 2010, 36(4), p. 486–498.
For suitable patients, family-based therapies are among the most effective – but are they the most cost-effective? Not always finds this US-focused review, which argues that to compete in today's financially sensitive health care system, treatments must deliver the most clinical outcomes per unit of cost.

STUDY 2011 HTM file
Specialist drug and alcohol services for young people – a cost benefit analysis

Frontier Economics.
[UK] Department for Education, 2011.
Study published by UK government estimates that every £1 spent on specialist substance misuse treatment for under-18s in Britain averts social costs totalling £4.66–£8.38.

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