The Addiction archive
 The Addiction archive

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The Addiction archive

Analyses of articles in the journal Addiction published by our partner the Society for the Study of Addiction starting with the most recently published article, totalling today 84 documents.

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REVIEW 2020 HTM file
Controlled drinking – non-abstinent versus abstinent treatment goals in alcohol use disorder: a systematic review, meta-analysis and meta-regression

Henssler J., Müller M., Carreira H. et al.
Addiction: 2020, early view
Comprehensive review and amalgamation of findings from studies enabling a comparison of controlled drinking versus abstinence as treatment goals concludes that even among diagnosably dependent drinkers, neither has the advantage in promoting low-risk (non-)drinking.

STUDY 2020 HTM file
Skin-cleaning among hospitalized people who inject drugs: a randomized controlled trial

Stein M.D., Phillips K.T., Herman D.S. et al.
Addiction: 2020, early view.
Serious bacterial infections are among the most common medical complications in people who inject drugs. Study asks whether an intervention targeting hand washing, injection site skin cleaning, and needle cleaning could reduce the burden, using as its key measure the rate of visits to the emergency department.

STUDY 2019 HTM file
Criminal justice outcomes over 5 years after randomization to buprenorphine-naloxone or methadone treatment for opioid use disorder

Evans E.A., Zhu Y., Yoo C. et al.
Addiction: 2019, 114, p. 1396–1404.
Can a limited period of being prescribed opiate-type medications generate longer term reductions in the criminal behaviour of patients dependent on illegal opiates like heroin? And of the two main medications – buprenorphine and methadone – which performs best? It seems a key factor is how well they retain patients in treatment.

STUDY 2019 HTM file
Modelling the combined impact of interventions in averting deaths during a synthetic-opioid overdose epidemic

Irvine M.A., Kuo M., Buxton J.A. et al.
Addiction: 2019, 114, p. 1602–1613.
In the Canadian province of British Columbia there was a rapid rise in overdose deaths from 2015, leading to the declaration of a public health emergency in 2016. The response rested on three key interventions: take-home naloxone, opioid substitution therapy, and drug consumption rooms. The province’s highly detailed surveillance data offered an opportunity to estimate their collective and individual impacts on opioid overdose deaths.

STUDY 2019 HTM file
Evaluating the cost-effectiveness of existing needle and syringe programmes in preventing hepatitis C transmission in people who inject drugs

Sweeney S., Ward Z., Platt L. et al.
Addiction: on-line advance publication, 2019.
What would happen to rates of infection with hepatitis C if we closed down all the needle exchanges? In three UK municipalities, the answers were predicted to be more infections, lost low-cost opportunities to improve and save lives, and in two of the areas, greater health-related costs overall. Conclusion was that these services are among the best investments UK health services can make. town

STUDY 2019 HTM file
Impact of the introduction and withdrawal of financial incentives on the delivery of alcohol screening and brief advice in English primary health care: an interrupted time-series analysis

O’Donnell A., Angus C., Hanratty B. et al.
Addiction: 2019, early view online.
The clearest impact of financial incentives to screen primary care patients in England was the plummeting screening rate after the incentives were withdrawn. If these results are applicable to England as a whole, over the following 21 months withdrawing the payments resulted in 603,719 fewer patients being screened for risky drinking and 27,439 fewer receiving brief advice.

REVIEW 2019 HTM file
Supervised consumption sites: a nuanced assessment of the causal evidence

Caulkins J.P., Pardo B., Kilmer B.
Addiction: 2019.
How high should the evidence bar be set when deciding whether to endorse drug consumption rooms?

REVIEW 2019 HTM file
Fetal alcohol spectrum disorder: a systematic review of the cost of and savings from prevention in the United States and Canada

Greenmyer J.R., Popova S., Klug M.G. et al.
Addiction: 2019, 115, p. 409–417.
Study set in Canada and the United States finds more than enough financial justification for expanding prevention of foetal alcohol spectrum disorders. But what does ‘expansion’ mean – universal prevention, or focusing resources on those most at risk?

STUDY 2019 HTM file
Do electronic health record prompts increase take-home naloxone administration for emergency department patients after an opioid overdose?

Marino R., Landau A., Lynch M. et al.
Addiction: 2019, 114, p. 1575–1581.
Emergency department physicians regularly treat people who have had an opioid overdose, but they may not be making the most of the opportunity to provide take-home naloxone. Can a prompt in the patients’ electronic health records boost prescribing of this lifesaving ‘overdose antidote’?

STUDY 2018 HTM file
The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom

Hickman M., Steer C., Tilling K. et al.
Addiction: 2018, 113(8), p. 1461–1476.
Buprenorphine may be associated with a lower risk of mortality than methadone among people engaged in opioid substitution treatment – but is the pattern of short treatment duration in the UK preventing maximal impact at a population level?

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