The Addiction archive

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The Addiction archive

Analyses of articles in the journal Addiction published by our partner the Society for the Study of Addiction starting with the most recently published article, totalling today 78 documents.

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STUDY 2019 HTM file
Evaluating the cost-effectiveness of existing needle and syringe programmes in preventing hepatitis C transmission in people who inject drugs

Sweeney S., Ward Z., Platt L. et al.
Addiction: on-line advance publication, 2019.
What would happen to rates of infection with hepatitis C if we closed down all the needle exchanges? In three UK municipalities, the answers were predicted to be more infections, lost low-cost opportunities to improve and save lives, and in two of the areas, greater health-related costs overall. Conclusion was that these services are among the best investments UK health services can make. town

STUDY 2019 HTM file
Impact of the introduction and withdrawal of financial incentives on the delivery of alcohol screening and brief advice in English primary health care: an interrupted time-series analysis

O’Donnell A., Angus C., Hanratty B. et al.
Addiction: 2019, early view online.
The clearest impact of financial incentives to screen primary care patients in England was the plummeting screening rate after the incentives were withdrawn. If these results are applicable to England as a whole, over the following 21 months withdrawing the payments resulted in 603,719 fewer patients being screened for risky drinking and 27,439 fewer receiving brief advice.

REVIEW 2019 HTM file
Supervised consumption sites: a nuanced assessment of the causal evidence

Caulkins J.P., Pardo B., Kilmer B.
Addiction: 2019.
How high should the evidence bar be set when deciding whether to endorse drug consumption rooms?

STUDY 2018 HTM file
The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom

Hickman M., Steer C., Tilling K. et al.
Addiction: 2018, 113(8), p. 1461–1476.
Buprenorphine may be associated with a lower risk of mortality than methadone among people engaged in opioid substitution treatment – but is the pattern of short treatment duration in the UK preventing maximal impact at a population level?

REVIEW 2018 HTM file
Baclofen: its effectiveness in reducing harmful drinking, craving, and negative mood. A meta-analysis

Rose A.K., Jones A.
Addiction: 2018, 113(8), p. 1396–1406.
With patchy evidence of the effectiveness of baclofen, and serious concerns about the medication’s safety, is it ‘premature’ for the muscle-relaxant to be prescribed as a treatment for alcohol use disorders?

STUDY 2018 HTM file
Impact of current and scaled-up levels of hepatitis C prevention and treatment interventions for people who inject drugs in three UK settings – what is required to achieve the WHO’s HCV elimination targets?

Ward Z., Platt L., Sweeney S. et al.
Addiction: 2018, 113, p. 1727–1738.
What would it take for the UK to meet the World Health Organization’s target of a 90% reduction in hepatitis C by 2030? According to projections in three diverse areas, current levels of harm reduction services are averting a great deal of transmission, and adding only moderate rates of treatment for hepatitis C would put Britain on course to achieve the elimination target.

STUDY 2017 HTM file
Does paying service providers by results improve recovery outcomes for drug misusers in treatment in England?

Jones A., Pierce M., Sutton M. et al.
Addiction: 2017, 113(2), p. 279–286.
Substance use treatment commissioned on a payment-by-results basis in England has been linked to higher rates of in-treatment abstinence and non-injecting than other commissioning models, but lower rates of treatment initiation and completion. Is this enough to support the policy?

REVIEW 2017 HTM file
Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders: a systematic review with direct and network meta-analyses on nalmefene, naltrexone, acamprosate, baclofen and topiramate

Palpacuer C., Duprez R., Huneau A. et al.
Addiction: 2017, in press.
In 2013 nalmefene was authorised for moderating drinking among patients not in need of detoxification, extending pharmacotherapy to less dependent drinkers. Though uniquely authorised for this purpose, this review found other (and probably cheaper) drugs have been just as or possibly more effective, but for none was there high quality evidence.

STUDY 2017 HTM file
The impacts of minimum alcohol pricing on alcohol attributable morbidity in regions of British Colombia, Canada with low, medium and high mean family income

Zhao J., Stockwell T.
Addiction: 2017, 112, p. 1942–1951.
Minimum price increases of alcoholic beverages in a Canadian province between 2002 and 2013 set the stage for a real-word study of minimum unit pricing. Reductions in alcohol-related hospital admissions, particularly in lower income areas, tentatively suggest that low income regions may experience the greatest health benefits of such a policy.

STUDY 2016 HTM file
Effectiveness of Scotland’s National Naloxone Programme for reducing opioid-related deaths: a before (2006–10) versus after (2011–13) comparison

Bird S.M., McAuley A., Perry S. et al.
Addiction: 2016, 111(5), p.883–891.
In 2011 Scotland became the first country to fund a national policy of distributing the opiate-blocker naloxone to prevent deaths involving opiate-type drugs. According to this evaluation it did prevent deaths where the effect was most likely to be seen – in the weeks after release from prison.


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