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You have found 212 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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STUDY 2020 HTM file
Comparative effectiveness of different treatment pathways for opioid use disorder

How do different pathways for the treatment of problem opioid use compare under real-world conditions? For US patients with health insurance, opioid substitution therapy was associated with the greatest risk reduction. However, its protective effect may not be fully realised while federal and insurance plan restrictions continue to limit access to this treatment option.

STUDY 2019 HTM file
Modelling the combined impact of interventions in averting deaths during a synthetic-opioid overdose epidemic

In the Canadian province of British Columbia there was a rapid rise in overdose deaths from 2015, leading to the declaration of a public health emergency in 2016. The response rested on three key interventions: take-home naloxone, opioid substitution therapy, and drug consumption rooms. The province’s highly detailed surveillance data offered an opportunity to estimate their collective and individual impacts on opioid overdose deaths.

STUDY 2019 HTM file
One opioid user saving another: the first study of an opioid overdose-reversal and naloxone distribution program addressing hard-to-reach drug scenes in Denmark

A Danish programme targeted potential bystanders of opioid overdoses, providing training and supplies of the ‘overdose antidote’ naloxone. People who use opioids were the most likely to intervene in an overdose situation, highlighting their positive role as “public health collaborators”.

HOT TOPIC 2020 HTM file
‘Dignity first’: improving the lives of homeless people who drink and take drugs

One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. Putting people with experiences of homelessness and substance use problems at the centre of social policy, this hot topic asks what solutions would look like if they prioritised saving lives and improving lives.

STUDY 2019 HTM file
Using interrupted time series analysis to measure the impact of legalized syringe exchange on HIV diagnoses in Baltimore and Philadelphia

Strong evidence from two US cities that moving from a blanket prohibition on possession of equipment for injecting illegal drugs to providing this equipment via legal needle and syringe programmes prevented thousands of HIV infections, resulting in large savings in the treatment of these infections.

REVIEW 2015 HTM file
Heroin on trial: systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction

The UK has a long history of prescribing heroin for the treatment of heroin dependence. What has research from six countries concluded about this intensive intervention intended for patients who would otherwise be considered ‘unresponsive’ to treatment?

STUDY 2019 HTM file
Evaluating peer-supported screening as a hepatitis C case-finding model in prisoners

For prison populations with multiple risk factors for acquiring hepatitis C, can a peer-supported screening programme improve the uptake of testing and treatment?

STUDY 2019 HTM file
Increased diagnosis and treatment of hepatitis C in prison by universal offer of testing and use of telemedicine

How can testing and treatment for hepatitis C be optimised in custodial settings? Prisons in the North East of England trialled new care pathways including a universal offer of testing using less invasive procedures and treatment facilitated by digital technology.

REVIEW 2019 HTM file
Supervised consumption sites: a nuanced assessment of the causal evidence

How high should the evidence bar be set when deciding whether to endorse drug consumption rooms?

REVIEW 2019 HTM file
The effectiveness of residential treatment services for individuals with substance use disorders: a systematic review

Has enough high-quality evidence accumulated over the past five years to improve confidence in the effectiveness of residential treatment?

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