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You have found 219 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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HOT TOPIC 2020 HTM file
‘Dignity first’: improving the lives of homeless people who drink and take drugs

One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. Putting people with experiences of homelessness and substance use problems at the centre of social policy, this hot topic asks what solutions would look like if they prioritised saving lives and improving lives.

STUDY 2019 HTM file
Using interrupted time series analysis to measure the impact of legalized syringe exchange on HIV diagnoses in Baltimore and Philadelphia

Strong evidence from two US cities that moving from a blanket prohibition on possession of equipment for injecting illegal drugs to providing this equipment via legal needle and syringe programmes prevented thousands of HIV infections, resulting in large savings in the treatment of these infections.

REVIEW 2015 HTM file
Heroin on trial: systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction

The UK has a long history of prescribing heroin for the treatment of heroin dependence. What has research from six countries concluded about this intensive intervention intended for patients who would otherwise be considered ‘unresponsive’ to treatment?

STUDY 2019 HTM file
Evaluating peer-supported screening as a hepatitis C case-finding model in prisoners

For prison populations with multiple risk factors for acquiring hepatitis C, can a peer-supported screening programme improve the uptake of testing and treatment?

STUDY 2019 HTM file
Increased diagnosis and treatment of hepatitis C in prison by universal offer of testing and use of telemedicine

How can testing and treatment for hepatitis C be optimised in custodial settings? Prisons in the North East of England trialled new care pathways including a universal offer of testing using less invasive procedures and treatment facilitated by digital technology.

REVIEW 2019 HTM file
Supervised consumption sites: a nuanced assessment of the causal evidence

How high should the evidence bar be set when deciding whether to endorse drug consumption rooms?

REVIEW 2019 HTM file
The effectiveness of residential treatment services for individuals with substance use disorders: a systematic review

Has enough high-quality evidence accumulated over the past five years to improve confidence in the effectiveness of residential treatment?

DOCUMENT 1987 HTM file
High time for harm reduction

Impelled by the injecting-related AIDS crisis, Merseyside was where harm reduction in the UK first took root. From there in 1987 came this groundbreaking call for a turn away from what was seen as a failed attempt to prevent use to mitigating the harm. Expressed modestly as a “prudent” suggestion, with Russell Newcombe’s essay, “harm reduction” had come of age.

STUDY 2018 HTM file
Effect of initiating drug treatment on the risk of drug-related poisoning death and acquisitive crime among offending heroin users

At issue was whether by successfully referring heroin users to treatment, probation services in England would protect them from fatal overdose and prevent drug-related crime. Yes to one, but not the other, were the answers; in fact, crime went up.

STUDY 2019 HTM file
Evaluating the cost-effectiveness of existing needle and syringe programmes in preventing hepatitis C transmission in people who inject drugs

What would happen to rates of infection with hepatitis C if we closed down all the needle exchanges? In three UK municipalities, the answers were predicted to be more infections, lost low-cost opportunities to improve and save lives, and in two of the areas, greater health-related costs overall. Conclusion was that these services are among the best investments UK health services can make. town


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