Matrix search results
You have found 212 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.
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STUDY 2018 HTM file
The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom
Buprenorphine may be associated with a lower risk of mortality than methadone among people engaged in opioid substitution treatment – but is the pattern of short treatment duration in the UK preventing maximal impact at a population level?
STUDY 2014 HTM file
Methadone induction in primary care for opioid dependence: a pragmatic randomized trial (ANRS Methaville)
From France the first study to randomly allocate patients to start methadone maintenance either in primary care or at a specialist centre found primary care more attractive to patients, and no less effective at reducing street-opioid use and promoting engagement and retention.
STUDY 2018 HTM file
A randomized, open label trial of methadone continuation versus forced withdrawal in a combined US prison and jail: findings at 12 months post-release
From the USA, a rare randomised trial found in favour of continuing methadone maintenance when patients entered prison rather than compulsory withdrawal. The potential benefits were most apparent in the near-100% continuation of protective treatment during the highly overdose-prone weeks after leaving prison.
Based on research, financial data and stakeholder surveys and testimonies, the UK government’s official drug policy advisers warn that without significant efforts to protect investment and quality, in England “loss of funding will result in the dismantling of a drug misuse treatment system that has brought huge improvement to the lives of people with drug and alcohol problems”.
REVIEW 2017 HTM file
Supervised dosing with a long-acting opioid medication in the management of opioid dependence
Trials challenge the need for the widely accepted policy of making opioid-dependent patients take their methadone or other opioid substitutes at the clinic or pharmacy, but ‘no difference’ findings may be due to the limitations of the research.
STUDY 2018 HTM file
Adult substance misuse statistics from the National Drug Treatment Monitoring System (NDTMS) 1 April 2016 to 31 March 2017
The annual accounting of the treatment caseload in England registers a continuing fall in total numbers and decreasing success with opiate users, while success with drinkers has increased and has for the last few years remained relatively high and stable. An ageing population of opiate users is the proposed explanation for the former trend – but why hasn’t a similarly ageing alcohol caseload also eroded success rates?
STUDY 2017 HTM file
Does paying service providers by results improve recovery outcomes for drug misusers in treatment in England?
Substance use treatment commissioned on a payment-by-results basis in England has been linked to higher rates of in-treatment abstinence and non-injecting than other commissioning models, but lower rates of treatment initiation and completion. Is this enough to support the policy?
STUDY 2017 HTM file
Recovery of infectious hepatitis C virus from injection paraphernalia: implications for prevention programs serving people who inject drugs
Resources spent on supplying ‘cookers’ and filters at needle exchanges may not help curb the spread of hepatitis C. Laboratory simulation suggests infections thought to be have been spread by sharing this equipment may be a proxy for transmission that occurs due to sharing blood-contaminated equipment for dividing drugs.
MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell E1: Local and national systems; Reducing harm
Seminal and key studies relating to local, regional and national systems for effectively and cost-effectively reducing harm.
MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell D1: Organisational functioning; Reducing harm
Seminal and key studies on the influence of the organisation on reducing drug-related harm.
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