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In the first study of its kind opiate-dependent prisoners in Norway were randomly allocated to a six-month implant which blocks the effects of heroin or to methadone which substitutes for heroin as a way of bridging the period after release. Among the few interested in either option, they led to equivalent reductions in opiate use and crime.
STUDY 2010 HTM file
Favorable mortality profile of naltrexone implants for opiate addiction
Few treatments for opiate addiction arouse as much controversy as naltrexone implants. Inserted under the skin, these block the effects of heroin for up to several months - for some, a magic bullet, for others, an unsafe and ethically dubious experiment. More evidence from Australia that the overdose death risk is less than with oral forms of the drug.
From the USA’s professional society for clinicians and allied professionals in the field of addiction medicine, comprehensive recommendations on how doctors can use medications to treat addiction to heroin and other opioids.
In the first randomised trial, implants which block opiate-type drugs for months helped heroin addicts in Norway avoid relapse after detoxification. If these or allied products gain a UK licence, they could help pave the way to abstinence for the minority of suitable addicts.
DOCUMENT 2017 HTM file
Drug misuse and dependence: UK guidelines on clinical management
Last published in 2007, there is no more important document for UK clinicians involved in treating problem drug use than the so-called ‘Orange guidelines’. This major update offers detailed guidance on the range of problems, settings and patients clinicians encounter, substantially informing judgements of what constitutes good medical practice.
STUDY 2002 PDF file 155Kb
Drug users who continue to inject still respond well to hepatitis C treatment
UK guidance from NICE and the Department of Health on the treatment of hepatitis C infection may need to be revised in the light of studies showing that drug users who continue to inject can nevertheless respond well to the treatment.
European and US studies show that methadone patients stick with therapy for hepatitis C disease and do as well as other patients, bolstering the case for drug services to encourage clients to consider diagnostic testing and therapy.
STUDY 2006 PDF file 139Kb
1 out of 61 hepatitis C positive treatment clients starts medical treatment
Despite testing positive for hepatitis C at a laboratory in Nottingham, just 1 out the 61 patients whose tests were requested by a drug or alcohol service ended up receiving treatment from six months to two and a half years after diagnosis, a dramatic failure to respond to the disease.
Brief interventions conducted by alcohol treatment specialists reduced alcohol-affected readmission rate by nearly half among patients admitted to a French emergency department when drunk or in need of withdrawal.
HOT TOPIC 2016 HTM file
The therapeutic potential of patients and clients
One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. The recovery agenda emphasises the transformation of problem substance users into solutions to those problems through peer support and involvement in their own care – but perhaps at a deeper level, the patient or client has always been the author of their own recovery.
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