You have found 175 entries. Sorted by the main topic addressed, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.
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STUDY 2012 HTM file
Randomized trial of standard methadone treatment compared to initiating methadone without counseling: 12-month findings
Up to a year after starting methadone treatment US patients offered virtually no counselling for the first four months were still doing as well as those offered regular counselling. But there is a hint that intensive and high quality counselling enabled more to safely leave treatment.
DOCUMENT 2014 HTM file
Time limiting opioid substitution therapy
Rather than being ‘parked’ on methadone, generally Britain’s heroin-addicted patients leave too soon to fully benefit, argue official government advisers on drug policy. Their report unambiguously countered concerns within the current UK government over methadone maintenance.
STUDY 2019 HTM file
Criminal justice outcomes over 5 years after randomization to buprenorphine-naloxone or methadone treatment for opioid use disorder
Can a limited period of being prescribed opiate-type medications generate longer term reductions in the criminal behaviour of patients dependent on illegal opiates like heroin? And of the two main medications – buprenorphine and methadone – which performs best? It seems a key factor is how well they retain patients in treatment.
REVIEW 2014 HTM file
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Authoritative analysis of clinically relevant trials of buprenorphine versus methadone maintenance for heroin dependence confirms that buprenorphine has less ‘holding power’, and that among patients who are retained, there are equivalent reductions in illegal drug use. But is methadone’s ‘stickiness’ an advantage or a liability?
STUDY 2011 HTM file
Investigating the effect on public behaviour of patients of a medically supervised injectable maintenance clinic
Addicts attending a clinic twice a day to take prescribed heroin seems like a recipe for an unwelcome increase in local drug-related disorder and nuisance, but in London the effect was to remove rather than add people to the troubling street-drinking population.
STUDY 2010 HTM file
Is heroin-assisted treatment effective for patients with no previous maintenance treatment? Results from a German randomised controlled trial
Uniquely among modern heroin prescribing trials, the trial in Germany was not confined to heroin-addicted patients who had done poorly on methadone, offering the opportunity to assess whether heroin should be reserved for these patients. The conclusion was that other patients too benefit more from injectable heroin than oral methadone.
STUDY 2010 HTM file
The Andalusian trial on heroin-assisted treatment: a 2 year follow-up
Heroin/cocaine addicts in Granada in Spain who were being prescribed heroin made greater sustained improvements in their illicit heroin use, crime and psychological health and showed signs of more social reintegration than patients who nearly three years before had been randomly allocated to methadone.
STUDY 2010 HTM file
The community impact of RIOTT, a medically supervised injectable maintenance clinic in south London
Addicts attending a clinic twice a day to take prescribed heroin seems like a recipe for an unwelcome increase in local drug-related disorder and nuisance, but given (as there usually will be) small numbers, experience in London was that not much changed.
REVIEW 2012 HTM file
New heroin-assisted treatment: Recent evidence and current practices of supervised injectable heroin treatment in Europe and beyond
Prescribing oral methadone to heroin addicts divides opinions, but prescribing injectable heroin elevates the controversy to another level. Fortunately we now have six randomised clinical trials involving over 1500 patients to ground us in the evidence – and this European Union review to pull it all together.
STUDY 2009 HTM file
Explaining the effectiveness of heroin-assisted treatment on crime reductions
This German study shows that heroin maintenance treatment can contribute to greater reductions in drug and property offences than methadone maintenance.
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