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You have found 141 entries after clicking the GO button or a search link in a hot topic. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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STUDY 2004 PDF file 159Kb
Methadone maintenance as low-cost lifesaver

US studies find that even when slow methadone detoxification is bolstered by psychosocial therapy and aftercare, methadone maintenance does better at prolonging the lives of opiate-dependent patients at relatively little extra cost.

STUDY 2004 PDF file 607Kb
Opiate antagonist treatment risks overdose

The most comprehensive recent study of serious medical incidents during and after treatment for opioid dependence highlighted the risk of overdose death when patients stop taking opiate-blocking drugs. In comparison, substitute prescribing was safer even after the patient had left treatment.

STUDY 2009 HTM file
Methadone patients in the therapeutic community: a test of equivalency

Are therapeutic communities incompatible with methadone maintenance? Not when staff have been prepared to accept and work with methadone patients and programmes adapted to accommodate them. Then patients stay as long and sustain abstinence from illegal drug use just as well as other residents.

STUDY 2008 HTM file
A study of methadone maintenance for male prisoners: 3-month postrelease outcomes

US study shows the value of immediate post-release transfer to an awaiting methadone maintenance slot for formerly heroin dependent prisoners willing to try this treatment but is less clear on the value of actually starting the treatment in prison.

STUDY 2007 HTM file
The costs and consequences of three policy options for reducing heroin dependency

Australian study addressing an issue greatly exercising the UK: do you get greater returns per £ from residential rehabilitation or from substitute prescribing? In terms of reduction in the frequency of heroin use, prescribing was one-and-a-half to three times more cost-effective.

STUDY 2004 PDF file 190Kb
First randomised trial finds methadone helps prisoners control drug use and infection risk

In Australia the first trial to randomly allocate prisoners seeking this treatment to methadone maintenance found substantial reductions in heroin use, injecting and syringe sharing, promising to avert infections and preserve lives.

STUDY 2004 PDF file 191Kb
Clinically relevant comparison supports buprenorphine as methadone alternative

A large scale Australian study which approximated recommended clinical procedures found buprenorphine roughly equivalent to methadone as a maintenance treatment for opiate dependence and also roughly as cost-effective.

STUDY 2004 PDF file 159Kb
Retention is not just about motivation

Being motivated enough to cut drug use before treatment entry leads to better outcomes, but even after taking this in to account, this huge US study found outcomes improved the longer patients stayed in residential or non-residential programmes.

REVIEW 2003 PDF file 925Kb
Role Reversal

Controversial, expensive, yet promising so much, interest is increasing in prescribing heroin to heroin addicts. Just five studies hold what answers there are to whether this can work, including a probably unrepeatable early British study.

OFFCUT 2003 PDF file 134Kb
Is your measure of success what matters to the client, or what matters to everyone else?

How a patient assesses their own well-being can be poorly related to conventional outcomes such as substance use. Using quality of life as a benchmark would often give a different impression of whether one treatment or service is better than another.


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