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You have found 141 entries after clicking the GO button or a search link in a hot topic. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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REVIEW 2014 HTM file
A review of buprenorphine diversion and misuse: the current evidence base and experiences from around the world

Practice-oriented review of what we know about the diversion (to other people) and misuse (mainly by injecting it) of buprenorphine used in the treatment of opiate dependence, featuring extended, practical guidance on how to identify and respond to these life-threatening behaviours as a therapeutic challenge rather than a disciplinary issue.

DOCUMENT 2014 HTM file
Community management of opioid overdose

Experts convened by the World Health Organization judged the risk-benefit profile to be strongly in favour of naloxone distribution to prevent opiate overdose deaths, but also cautioned that this “does not address the underlying causes of opioid overdose”.

STUDY 2010 HTM file
Were the changes to Sweden’s maintenance treatment policy 2000–06 related to changes in opiate-related mortality and morbidity?

Ironically, the fact that opiate substitute prescribing has been opposed and limited in Sweden has meant that country has been able provide solid evidence of its lifesaving potential. This study concluded that easing the restrictions was associated with and may have led to fewer opiate-related deaths.

REVIEW 2011 HTM file
A systematic review and meta-analysis of interventions to prevent hepatitis C virus infection in people who inject drugs

Despite the challenges, review confirms that hepatitis C infection can be prevented among injectors, but it takes multi-component strategies with elements such as substitute prescribing to reduce or eliminate drug injection, treatment of infection, and enabling safe injection practices by providing sterile injecting equipment and behaviour-change counselling.

STUDY 2014 HTM file
Drugs: international comparators

After seeing how drug policy worked overseas, UK government ministers and officials returned saying, “there is no apparent correlation between the ‘toughness’ of a country’s approach and the prevalence of adult drug use”, and that “better health outcomes for drug users cannot be shown to be a direct result of the enforcement approach”.

STUDY 2013 HTM file
Increased somatic morbidity in the first year after leaving opioid maintenance treatment: results from a Norwegian cohort study

From Norway, strong evidence that being in a methadone or buprenorphine maintenance programme protects heroin-dependent patients from drug-related ill-health including life-threatening overdoses and infections, even if the treatment has not completely subdued illegal drug use.

DOCUMENT 2014 HTM file
Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations

Consolidates WHO guidance on HIV prevention, diagnosis, treatment and care for key populations including prisoners and people who inject drugs. Strongly advocates universal access of injectors to needle exchange and of dependent opioid users to indefinite, high dose methadone and buprenorphine maintenance.

STUDY 1995 HTM file
An evaluation of private methadone clinics

Comparison of three Australian clinics highlights the importance of good organisation and an ethos of individualised treatment and care for patients, rather than acting as a more or less efficient ‘methadone dispensary’.

REVIEW 2014 HTM file
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence

Authoritative analysis of clinically relevant trials of buprenorphine versus methadone maintenance for heroin dependence confirms that buprenorphine has less ‘holding power’, and that among patients who are retained, there are equivalent reductions in illegal drug use. But is methadone’s ‘stickiness’ an advantage or a liability?

DOCUMENT 2013 HTM file
Rewarding virtue

Can we dispense with counselling, therapy, treatment as we know it, and just punish or deprive patients of rewards when they use substances in undesired ways, and reward them when they behave as we/they would wish? British services are trialling an approach about which many clinicians express major ethical concerns – contingency management.


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