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You have found 23 entries. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.
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STUDY 2015 HTM file
Risk of mortality on and off methadone substitution treatment in primary care: a national cohort study
Primary care methadone patients in Ireland were nearly four times more likely to die during periods out of treatment; the first few weeks after leaving were the peak risk period. The study’s support for unbroken, long-term treatment runs counter to recent UK government policy.
STUDY 2010 HTM file
Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK
This British study concluded that it takes extended opiate substitute prescribing to realise the treatment's life-saving potential. The implication is that the current push to get people off methadone sooner could cost lives.
DOCUMENT 2013 HTM file
Delivering recovery. Independent expert review of opioid replacement therapies in Scotland
An expert committee responds to the Scottish government’s concerns over the role of methadone prescribing in helping patients along the Road to Recovery signposted in the national strategy. On the ground, that road was often barely constructed but methadone was not the problem, rather the failure to optimise programmes for recovery.
STUDY 2010 HTM file
Unobserved versus observed office buprenorphine/naloxone induction: a pilot randomized clinical trial
Having for several hours to medically monitor opiate-addicted patients starting buprenorphine maintenance is a major impediment to spreading the benefits of the treatment, but this first randomised trial suggests that many patients can manage the process safely at home.
STUDY 2010 HTM file
Home- versus office-based buprenorphine inductions for opioid-dependent patients
Is is safe and will heroin-dependent patients complete the process and stay in treatment if they start buprenorphine maintenance at home rather than being observed and doses adjusted at the clinic? This US study suggests this is feasible, saving time for all concerned, but also hints at possible (in this case, rare) complications.
STUDY 2011 HTM file
Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence
From the USA, the first large study to randomly allocate patients dependent on prescription opioids to different treatments found that despite wanting to detoxify, all but a few relapsed after withdrawal from substitute medication; more intensive and specialist counselling did not help.
DOCUMENT 2011 HTM file
Buprenorphine/naloxone for opioid dependence: clinical practice guideline
Though tailored for Canada, these guidelines from an internationally respected centre offer valuable guidance to clinicians in Britain and elsewhere on a form of the main alternative to methadone for the maintenance treatment of addiction to heroin and allied drugs, one whose greater safety counterbalances greater cost.
ABSTRACT 2011 HTM file
Guidance for the use of substitute prescribing in the treatment of opioid dependence in primary care
Evidence-based guidance for British GPs on how to withdraw heroin and other opioid addicts from opiate-type drugs or to maintain them by long-term prescribing of legal substitutes, with a focus on the use methadone and buprenorphine, the main medications used for these purposes in the UK.
STUDY 2010 HTM file
The National Drug Related Deaths Database (Scotland) report 2009
New database offering in-depth information on drug deaths in Scotland reveals that 60% of cases had been in contact with drug treatment services, nearly 40% in the past six months, suggesting that there had been chances to intervene which for these patients had been insufficient to avoid death.
STUDY 2004 PDF file 105Kb
British GPs as effective as specialist methadone clinics
A two-year follow-up of opiate dependent patients sampled by the national English NTORS study showed that experienced or supported GPs can provide methadone maintenance treatment at least as effectively as specialist clinics.
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