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You have found 23 entries. Sorted by the main topic addressed, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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MATRIX CELL 2018 HTM file
Drug Treatment Matrix cell D3: Organisational functioning; Medical treatment

Seminal and key studies on how treatment organisations affect the implementation and effectiveness of medical interventions and treatment in medical settings. Focus is on UK and US understandings of what counts as a ‘recovery-oriented’ service and on US, Australian and Canadian studies which discovered and validated elements of these visions even before they were articulated.

STUDY 2010 HTM file
The National Drug Related Deaths Database (Scotland) report 2009

New database offering in-depth information on drug deaths in Scotland reveals that 60% of cases had been in contact with drug treatment services, nearly 40% in the past six months, suggesting that there had been chances to intervene which for these patients had been insufficient to avoid death.

STUDY 2001 PDF file 188Kb
Outcomes from GP methadone maintenance in Britain match those from specialist clinics

Findings from Liverpool make a valuable addition to a limited UK evidence base confirming that outcomes from addiction treatment by well-supported GPs are at least as good as those achieved by specialist clinics.

STUDY 2004 PDF file 105Kb
British GPs as effective as specialist methadone clinics

A two-year follow-up of opiate dependent patients sampled by the national English NTORS study showed that experienced or supported GPs can provide methadone maintenance treatment at least as effectively as specialist clinics.

STUDY 2010 HTM file
Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK

This British study concluded that it takes extended opiate substitute prescribing to realise the treatment's life-saving potential. The implication is that the current push to get people off methadone sooner could cost lives.

DOCUMENT 2013 HTM file
Delivering recovery. Independent expert review of opioid replacement therapies in Scotland

An expert committee responds to the Scottish government’s concerns over the role of methadone prescribing in helping patients along the Road to Recovery signposted in the national strategy. On the ground, that road was often barely constructed but methadone was not the problem, rather the failure to optimise programmes for recovery.

STUDY 2015 HTM file
Risk of mortality on and off methadone substitution treatment in primary care: a national cohort study

Primary care methadone patients in Ireland were nearly four times more likely to die during periods out of treatment; the first few weeks after leaving were the peak risk period. The study’s support for unbroken, long-term treatment runs counter to recent UK government policy.

STUDY 2018 HTM file
The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom

Buprenorphine may be associated with a lower risk of mortality than methadone among people engaged in opioid substitution treatment – but is the pattern of short treatment duration in the UK preventing maximal impact at a population level?

REVIEW 2002 PDF file 1258Kb
There is an alternative: buprenorphine maintenance

A team led by one of the most respected authorities in the world on drug-based treatments for opiate dependence assesses the evidence for a drug emerging as the most promising alternative to methadone.

STUDY 2010 HTM file
Unobserved versus observed office buprenorphine/naloxone induction: a pilot randomized clinical trial

Having for several hours to medically monitor opiate-addicted patients starting buprenorphine maintenance is a major impediment to spreading the benefits of the treatment, but this first randomised trial suggests that many patients can manage the process safely at home.

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