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You have found 31 entries. Starting with analyses of the most recently published documents, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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MATRIX CELL 2017 HTM file
Drug Matrix cell C1: Management/supervision: Reducing harm

Seminal and key studies on the role of management and supervision in reducing harm associated with illegal drug use.

REVIEW 2016 HTM file
Preventing opioid overdose deaths with take-home naloxone

To aid policymaking, experts commissioned by the European Union’s drug misuse monitoring centre review the evidence and offer guidance on the provision of the medication naloxone, which reverses the effects of drugs like heroin, helping to prevent overdoses becoming fatal.

DOCUMENT 2016 HTM file
Harm reduction database Wales: take home naloxone 2015–16

Report charting the roll-out of ‘take-home naloxone’ in Wales up to 2016, a harm-reduction measure implemented to prevent deaths involving opiate-type drugs.

STUDY 2016 HTM file
Effectiveness of Scotland’s National Naloxone Programme for reducing opioid-related deaths: a before (2006–10) versus after (2011–13) comparison

In 2011 Scotland became the first country to fund a national policy of distributing the opiate-blocker naloxone to prevent deaths involving opiate-type drugs. According to this evaluation it did prevent deaths where the effect was most likely to be seen – in the weeks after release from prison.

REVIEW 2016 HTM file
Are take-home naloxone programmes effective? Systematic review utilizing application of the Bradford Hill criteria

How confident can we be that take-home naloxone programmes are effective without the ‘gold standard’ randomised trial? Judged against nine criteria for establishing the presumption of causality, evidence that the provision of naloxone reduces overdose-related deaths among opioid users.

DOCUMENT 2015 HTM file
American Society of Addiction Medicine (ASAM) national practice guideline for the use of medications in the treatment of addiction involving opioid use

From the USA’s professional society for clinicians and allied professionals in the field of addiction medicine, comprehensive recommendations on how doctors can use medications to treat addiction to heroin and other opioids.

DOCUMENT 2014 HTM file
Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations

Consolidates WHO guidance on HIV prevention, diagnosis, treatment and care for key populations including prisoners and people who inject drugs. Strongly advocates universal access of injectors to needle exchange and of dependent opioid users to indefinite, high dose methadone and buprenorphine maintenance.

DOCUMENT 2014 HTM file
Community management of opioid overdose

Experts convened by the World Health Organization judged the risk-benefit profile to be strongly in favour of naloxone distribution to prevent opiate overdose deaths, but also cautioned that this “does not address the underlying causes of opioid overdose”.

STUDY 2013 HTM file
Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis

This real-world implementation of overdose education and nasal naloxone distribution in Massachusetts illustrates the life-saving potential of these programmes.

STUDY 2013 HTM file
Cost-effectiveness of distributing naloxone to heroin users for lay overdose reversal

The first simulation of the cost-effectiveness of supplying naloxone kits to heroin users to enable them to prevent overdose deaths estimates that in the US context these programmes would be well within the range considered a cost-effective health intervention. Findings are likely to broadly apply to the UK, one weak link being whether drug users given the kits actually carry them around.


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