Hot topic search results

Effectiveness bank home page. Opens new window Hot topic search results

You have found 95 entries after clicking the GO button or a search link in a hot topic. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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STUDY 2018 HTM file
“Once I’d done it once it was like writing your name”: Lived experience of take-home naloxone administration by people who inject drugs

Important implications for overdose prevention policy and practice in Scotland and the UK from this qualitative study which provides the first detailed insights into how people who inject drugs experience administering naloxone rescue kits.

STUDY 2018 HTM file
The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom

Buprenorphine may be associated with a lower risk of mortality than methadone among people engaged in opioid substitution treatment – but is the pattern of short treatment duration in the UK preventing maximal impact at a population level?

HOT TOPIC 2018 HTM file
Ethics and evidence on naltrexone treatment of offenders

‘Hot topics’ offer background and analysis on important issues which sometimes generate heated debate. Opinion is sharply divided on the ethics and effectiveness of pressuring opioid-dependent offenders to take the opiate-blocker naltrexone. Especially sharp is the controversy over long-acting products not approved for medical practice in the UK. Do they constitute an unacceptable infringement of autonomy, or is forcing them on some offenders as caring as holding back someone about to (by choice or not) walk off a cliff?

STUDY 2016 HTM file
Extended-release naltrexone to prevent opioid relapse in criminal justice offenders

Added to basic counselling alone, monthly injections of the opioid-blocking drug naltrexone helped prevent relapse among US offenders with a history of opioid dependence recently released from prison or under criminal justice supervision in the community – findings most applicable to those who prefer opioid-free to opioid-maintenance treatments.

STUDY 2014 HTM file
Methadone induction in primary care for opioid dependence: a pragmatic randomized trial (ANRS Methaville)

From France the first study to randomly allocate patients to start methadone maintenance either in primary care or at a specialist centre found primary care more attractive to patients, and no less effective at reducing street-opioid use and promoting engagement and retention.

STUDY 2018 HTM file
A randomized, open label trial of methadone continuation versus forced withdrawal in a combined US prison and jail: findings at 12 months post-release

From the USA, a rare randomised trial found in favour of continuing methadone maintenance when patients entered prison rather than compulsory withdrawal. The potential benefits were most apparent in the near-100% continuation of protective treatment during the highly overdose-prone weeks after leaving prison.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell E1: Local and national systems; Reducing harm

Seminal and key studies relating to local, regional and national systems for effectively and cost-effectively reducing harm.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell D1: Organisational functioning; Reducing harm

Seminal and key studies on the influence of the organisation on reducing drug-related harm.

MATRIX CELL 2017 HTM file
Drug Matrix cell C1: Management/supervision: Reducing harm

Seminal and key studies on the role of management and supervision in reducing harm associated with illegal drug use.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell B1: Practitioners; Reducing harm

Seminal and key studies on the impact of the practitioner on harm reduction. Trust emerges as a fundamental ingredient to harm reduction work with users of illegal drugs. Reconceptualise needle exchanges as safe havens in a largely rejecting world, and explore why a Philadelphia methadone counsellor stood out – for the wrong reasons.


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