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STUDY 2010 HTM file
Were the changes to Sweden’s maintenance treatment policy 2000–06 related to changes in opiate-related mortality and morbidity?

Ironically, the fact that opiate substitute prescribing has been opposed and limited in Sweden has meant that country has been able provide solid evidence of its lifesaving potential. This study concluded that easing the restrictions was associated with and may have led to fewer opiate-related deaths.

DOCUMENT 2014 HTM file
Time limiting opioid substitution therapy

Rather than being ‘parked’ on methadone, generally Britain’s heroin-addicted patients leave too soon to fully benefit, argue official government advisers on drug policy. Their report unambiguously countered concerns within the current UK government over methadone maintenance.

STUDY 2013 HTM file
Increased somatic morbidity in the first year after leaving opioid maintenance treatment: results from a Norwegian cohort study

From Norway, strong evidence that being in a methadone or buprenorphine maintenance programme protects heroin-dependent patients from drug-related ill-health including life-threatening overdoses and infections, even if the treatment has not completely subdued illegal drug use.

DOCUMENT 2014 HTM file
Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations

Consolidates WHO guidance on HIV prevention, diagnosis, treatment and care for key populations including prisoners and people who inject drugs. Strongly advocates universal access of injectors to needle exchange and of dependent opioid users to indefinite, high dose methadone and buprenorphine maintenance.

STUDY 2010 HTM file
Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK

This British study concluded that it takes extended opiate substitute prescribing to realise the treatment's life-saving potential. The implication is that the current push to get people off methadone sooner could cost lives.

REVIEW 2010 HTM file
Gamma-hydroxybutyrate (GHB) for treatment of alcohol withdrawal and prevention of relapses

Can one of the UK’s most notorious ‘club drugs’ help alcoholic patients withdraw from and stay away from alcohol? The answer from this authoritative review is that probably it can, but not well enough to displace safer and less abuse-prone alternatives.

STUDY 2012 HTM file
The impact of take-home naloxone distribution and training on opiate overdose knowledge and response: an evaluation of the THN Project in Wales

The evaluation which led to the Welsh national programme to distribute naloxone to opiate users and their associates to curb rising overdose deaths, one of several UK studies to give momentum to this peer-based strategy.

STUDY 2011 HTM file
Impact of training for healthcare professionals on how to manage an opioid overdose with naloxone: effective, but dissemination is challenging

Training for addiction treatment staff in managing overdose using naloxone, seeded in London by the National Addiction Centre, 'cascaded' to other staff and to patients at a disappointingly slow pace; on average each clinician trainee trained one drug user every 11 months.

REVIEW 2012 HTM file
Consideration of naloxone

The UK’s official drugs law and policy advisory body recommends that alongside training, the opiate-blocker naloxone be made more widely and easily available to enable drug users and those who work and associate with them to prevent opiate overdose deaths.

DOCUMENT 2013 HTM file
Community loses from failure to offer maintenance prescribing in prisons

An international team of experts has argued that failure to implement effective opioid maintenance programmes in prison represents an important missed opportunity to engage high-risk drug users in treatment, at possibly substantial costs to the individuals and to the community. Is Britain too losing out, and how does the future look?

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