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You have found 92 entries after clicking the GO button or a search link in a hot topic. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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DOCUMENT 2014 HTM file
Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations

Consolidates WHO guidance on HIV prevention, diagnosis, treatment and care for key populations including prisoners and people who inject drugs. Strongly advocates universal access of injectors to needle exchange and of dependent opioid users to indefinite, high dose methadone and buprenorphine maintenance.

STUDY 2010 HTM file
Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK

This British study concluded that it takes extended opiate substitute prescribing to realise the treatment's life-saving potential. The implication is that the current push to get people off methadone sooner could cost lives.

REVIEW 2010 HTM file
Gamma-hydroxybutyrate (GHB) for treatment of alcohol withdrawal and prevention of relapses

Can one of the UK’s most notorious ‘club drugs’ help alcoholic patients withdraw from and stay away from alcohol? The answer from this authoritative review is that probably it can, but not well enough to displace safer and less abuse-prone alternatives.

STUDY 2012 HTM file
The impact of take-home naloxone distribution and training on opiate overdose knowledge and response: an evaluation of the THN Project in Wales

The evaluation which led to the Welsh national programme to distribute naloxone to opiate users and their associates to curb rising overdose deaths, one of several UK studies to give momentum to this peer-based strategy.

STUDY 2011 HTM file
Impact of training for healthcare professionals on how to manage an opioid overdose with naloxone: effective, but dissemination is challenging

Training for addiction treatment staff in managing overdose using naloxone, seeded in London by the National Addiction Centre, 'cascaded' to other staff and to patients at a disappointingly slow pace; on average each clinician trainee trained one drug user every 11 months.

REVIEW 2012 HTM file
Consideration of naloxone

The UK’s official drugs law and policy advisory body recommends that alongside training, the opiate-blocker naloxone be made more widely and easily available to enable drug users and those who work and associate with them to prevent opiate overdose deaths.

DOCUMENT 2013 HTM file
Community loses from failure to offer maintenance prescribing in prisons

An international team of experts has argued that failure to implement effective opioid maintenance programmes in prison represents an important missed opportunity to engage high-risk drug users in treatment, at possibly substantial costs to the individuals and to the community. Is Britain too losing out, and how does the future look?

DOCUMENT 2012 HTM file
An introduction to extended-release injectable naltrexone for the treatment of people with opioid dependence

Few treatments arouse as much controversy as long-acting naltrexone implants or injections which promise to block the effects of heroin for up to several months. But in the USA the injected form has been licensed for treating opioid dependence. This document offers official US clinical guidance to doctors undertaking the treatment.

STUDY 2010 HTM file
Impact of supervision of methadone consumption on deaths related to methadone overdose (1993-2008): analyses using OD4 index in England and Scotland

Introduced in Scotland and England in the mid-late 1990s to prevent overdose, did supervised consumption of methadone really make methadone maintenance safer? After accounting for increased prescribing, this analysis concludes that it did curb methadone-related deaths.

STUDY 2012 HTM file
A randomized trial of methadone initiation prior to release from incarceration

This US randomised trial in Rhode Island among formerly opiate dependent prisoners found that starting methadone treatment in prison radically improved treatment uptake on release and reduced heroin and cocaine use over the following six months, confirming results from Baltimore.


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