Matrix search results

You have found 58 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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HOT TOPIC 2018 HTM file
Opiate-blocking implants: magic bullet or dangerous experiment?

‘Hot topics’ offer background and analysis on important issues which sometimes generate heated debate. Opinion is sharply divided on the ethics and effectiveness of long-acting implanted or injected opiate-blocking medications, products not approved for medical practice in the UK, but which some see as a major breakthroughs in overcoming addiction to heroin and allied drugs.

STUDY 2015 HTM file
A double blind, placebo controlled trial of modafinil for the treatment of cocaine dependence without co-morbid alcohol dependence

Modafinil is a mild stimulant which it is hoped might plug the gap in effective pharmacotherapies for dependence on cocaine. Though this trial found that it promoted abstinence from cocaine, others have not, and its inconsistent benefits have been seen as failing to outweigh the drug’s side effects.

MATRIX CELL 2018 HTM file
Drug Treatment Matrix cell C3: Management/supervision; Medical treatment

Seminal and key studies on the role of management and supervision in medical interventions and treatment in medical settings. Commentary considers how medication-based treatment can be (re)oriented to long-term recovery, the importance of the right dose, and whether we can we dispense with all but minimal counselling and therapy and supervised consumption of medications like methadone.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell C2: Management/supervision; Generic and cross-cutting issues

Key studies on the role of management and supervision across psychosocial and medical treatments of problem drug use. Highlights that “Manners Matter”, asks, “Is there anything more instructive than being the patient?”, explores the role of patient choice and preferences in treatment planning, and queries the ubiquitous stages of change model. See the rest of row 2 of the matrix for more on features common to psychosocial and medical treatments.

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell A2: Interventions; Generic and cross-cutting issues

Seminal and key studies on features common to psychosocial therapy/support and medical treatment. Investigates where treatment is aiming to get to in the form of ‘recovery’, where it starts from as depicted in the brain-disease model of addiction, and the politics of the two most important British drug treatment studies.

DOCUMENT 2017 HTM file
Drug misuse and dependence: UK guidelines on clinical management

Last published in 2007, there is no more important document for UK clinicians involved in treating problem drug use than the so-called ‘Orange guidelines’. This major update offers detailed guidance on the range of problems, settings and patients clinicians encounter, substantially informing judgements of what constitutes good medical practice.

STUDY 2015 HTM file
Changing patterns of substance misuse in adult prisons and service responses

Inspection findings on individual prisons were supplemented by fieldwork in eight prisons in 2014 to generate an overall picture of drug use and responses to it in prisons and England and Wales. In the face of rapidly changing and varied drug use patterns, policy and operational responses were seen as insufficiently flexible and dynamic, though treatment had dramatically improved.

STUDY 2014 HTM file
Effectiveness of training family physicians to deliver a brief intervention to address excessive substance use among young patients: a cluster randomized controlled trial

Can a brief intervention delivered by trained GPs impact on young patients’ excessive drinking and cannabis use? Set in French-speaking Switzerland, this study examines outcomes over a 12-month period.

HOT TOPIC 2017 HTM file
Overdose deaths in the UK: crisis and response

One of our selection of hot topics – important issues which sometimes generate heated debate. Why did the fall in UK drug overdose deaths in 2009 to 2012 so decisively reverse in the following years? A life-threatening turn away from harm reduction, or simply an ageing population of heroin users?

STUDY 2015 HTM file
Impact of treatment for opioid dependence on fatal drug-related poisoning: a national cohort study in England

Implication of this English study is that to save the lives of people dependent on heroin or similar drugs, they should be engaged and retained in substitute prescribing programmes like methadone maintenance until there is little risk of their relapsing after leaving. Shortly after leaving residential/inpatient settings was the highest risk period.

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