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You have found 62 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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STUDY 2012 HTM file
Housing first for severely mentally ill homeless methadone patients

Homelessness is a significant obstacle to regular participation in methadone maintenance treatment, particularly among people leaving prison. This study in a major US city examines whether a ‘housing first’ programme could improve outcomes among this cohort.

REVIEW 2019 HTM file
The effectiveness of residential treatment services for individuals with substance use disorders: a systematic review

Has enough high-quality evidence accumulated over the past five years to improve confidence in the effectiveness of residential treatment?

STUDY 2019 HTM file
Capital depreciation: the lack of recovery capital and post-release support for prisoners leaving the Drug Recovery Wings in England and Wales

While drug recovery wings were specifically designed to facilitate recovery from drug and alcohol problems among prisoners, this small study found that the sharp drop-off in support when they returned to the community ended many recovery journeys prematurely.

STUDY 2019 HTM file
Efficacy and cost-effectiveness of an adjunctive personalised psychosocial intervention in treatment-resistant maintenance opioid agonist therapy: a pragmatic, open-label, randomised controlled trial

Instead of a set programme, a clinic in London tried offering methadone or buprenorphine patients still using heroin or cocaine a selection from a suite of well-supported psychological interventions tailored to the patient and then systematically re-tailored in the light of how they responded. It worked – but did it work well enough, and would the findings be replicated in more typical circumstances?

MATRIX CELL 2018 HTM file
Drug Treatment Matrix cell D5: Organisational functioning; Safeguarding the community

Key research on the influence of the treatment organisation on the effectiveness of drug treatment in the criminal justice system and allied settings. Asks whether the criminal justice context enhances or limits treatment (perhaps both), whether quality is better in smaller services, and whether treatment services should see themselves as family services.

REVIEW 2017 HTM file
Supervised dosing with a long-acting opioid medication in the management of opioid dependence

Trials challenge the need for the widely accepted policy of making opioid-dependent patients take their methadone or other opioid substitutes at the clinic or pharmacy, but ‘no difference’ findings may be due to the limitations of the research.

STUDY 2014 HTM file
Treatment retention, drug use and social functioning outcomes in those receiving 3 months versus 1 month of supervised opioid maintenance treatment. Results from the Super C randomized controlled trial

A randomised trial conducted in England found that the (at the time) recommended three months of supervised consumption of prescribed opioid substitutes like methadone conferred no significant advantages over supervising only for up to the first four weeks of treatment, but the findings applied only to the minority of patients for whom random allocation was thought feasible and safe.

STUDY 2017 HTM file
The evaluation of the Drug Recovery Wing pilots: Final report

The final piece of the Drug Recovery Wing evaluation jigsaw, focusing on the process and impact of implementing the model in eight men’s and two women’s prisons in England and Wales.

DOCUMENT 2017 HTM file
Drug misuse and dependence: UK guidelines on clinical management

Last published in 2007, there is no more important document for UK clinicians involved in treating problem drug use than the so-called ‘Orange guidelines’. This major update offers detailed guidance on the range of problems, settings and patients clinicians encounter, substantially informing judgements of what constitutes good medical practice.

STUDY 2015 HTM file
Changing patterns of substance misuse in adult prisons and service responses

Inspection findings on individual prisons were supplemented by fieldwork in eight prisons in 2014 to generate an overall picture of drug use and responses to it in prisons and England and Wales. In the face of rapidly changing and varied drug use patterns, policy and operational responses were seen as insufficiently flexible and dynamic, though treatment had dramatically improved.


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