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You have found 124 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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STUDY 2004 PDF file 191Kb
Clinically relevant comparison supports buprenorphine as methadone alternative

A large scale Australian study which approximated recommended clinical procedures found buprenorphine roughly equivalent to methadone as a maintenance treatment for opiate dependence and also roughly as cost-effective.

REVIEW 2008 HTM file
International review and UK guidance weigh merits of buprenorphine versus methadone maintenance

Analysis which informed new UK guidelines on the maintenance treatment of opiate dependence concludes that buprenorphine has slightly less 'holding power' than methadone but equivalent suppression of opiate use.

REVIEW 2003 PDF file 925Kb
Role Reversal

Controversial, expensive, yet promising so much, interest is increasing in prescribing heroin to heroin addicts. Just five studies hold what answers there are to whether this can work, including a probably unrepeatable early British study.

STUDY 2003 PDF file 151Kb
'Most compelling evidence yet' that injecting rooms reduce overdose deaths

A review of all 19 drug consumption rooms in Germany commissioned by the Ministry of Health concluded that they had significantly contributed to reductions in drug-related deaths.

STUDY 2008 HTM file
Adequate needle exchange helps prevent bacterial as well as viral infections

US study suggest that needle exchanges which make adequate supplies of injecting equipment plus advice easily accessible not only prevent viral infections but also bacterial infections and abscesses, relieving a major burden on health services.

STUDY 2002 PDF file 1321Kb
The grand design: lessons from DATOS

US drug treatment was under fire, over-stretched and facing the new challenge of crack cocaine when the huge DATOS study set out to test whether it was still delivering benefits, how it worked, and how it could be made better. Truly essential reading.

STUDY 2002 PDF file 172Kb
Group cognitive-behavioural therapy can work well and save money

Brazilian clinic found that for both drinkers and drug users, cognitive-behavioural therapy worked as well in a group as an individual format with potential cost-savings. Extended text documents similar studies.

STUDY 2001 PDF file 98Kb
Opiate detoxification: spending more may save long term

British study suggests that inadequately supervised outpatient programmes may be a waste of money and that costly specialist inpatient programmes are not necessarily more costly per abstinent outcome, but methodological flaws cloud the picture.

STUDY 2001 PDF file 107Kb
Injectable methadone maintenance suitable for more severely affected heroin addicts

Conducted in London, the first study to randomise opiate dependent patients to injectable versus oral methadone maintenance suggested that the injectable option is preferable for addicts with relatively severe health and psychological problems.

STUDY 2000 PDF file 166Kb
Rare attempt to compare cost-effectiveness of different treatments for different clients

Studies of the cost-effectiveness of addiction treatment in Ohio suggest that per $, short intensive programmes deliver the best abstinence returns for severely addicted patients, less intensive outpatient programmes for patients using less frequently.


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