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You have found 124 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Sorted by the main topic addressed, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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REVIEW 2015 HTM file
Heroin on trial: systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction

The UK has a long history of prescribing heroin for the treatment of heroin dependence. What has research from six countries concluded about this intensive intervention intended for patients who would otherwise be considered ‘unresponsive’ to treatment?

DOCUMENT 2017 HTM file
Drug misuse and dependence: UK guidelines on clinical management

Last published in 2007, there is no more important document for UK clinicians involved in treating problem drug use than the so-called ‘Orange guidelines’. This major update offers detailed guidance on the range of problems, settings and patients clinicians encounter, substantially informing judgements of what constitutes good medical practice.

STUDY 2012 HTM file
Usefulness of brief intervention for patients admitted to emergency services for acute alcohol intoxication

Brief interventions conducted by alcohol treatment specialists reduced alcohol-affected readmission rate by nearly half among patients admitted to a French emergency department when drunk or in need of withdrawal.

STUDY 2002 PDF file 172Kb
Group cognitive-behavioural therapy can work well and save money

Brazilian clinic found that for both drinkers and drug users, cognitive-behavioural therapy worked as well in a group as an individual format with potential cost-savings. Extended text documents similar studies.

DOCUMENT 2007 HTM file
Drug misuse in over 16s: psychosocial interventions

After examining the evidence for psychosocial therapies for problem drug use, the UK’s official health advisers recommend behavioural couples therapy and contingency management, argue against cognitive-behavioural therapies, and pose residential rehabilitation as a last resort – in some respects surprising and controversial recommendations.

STUDY 2019 HTM file
Efficacy and cost-effectiveness of an adjunctive personalised psychosocial intervention in treatment-resistant maintenance opioid agonist therapy: a pragmatic, open-label, randomised controlled trial

Instead of a set programme, a clinic in London tried offering methadone or buprenorphine patients still using heroin or cocaine a selection from a suite of well-supported psychological interventions tailored to the patient and then systematically re-tailored in the light of how they responded. It worked – but did it work well enough, and would the findings be replicated in more typical circumstances?

MATRIX CELL 2017 HTM file
Drug Treatment Matrix cell B1: Practitioners; Reducing harm

Seminal and key studies on the impact of the practitioner on harm reduction. Trust emerges as a fundamental ingredient to harm reduction work with users of illegal drugs. Reconceptualise needle exchanges as safe havens in a largely rejecting world, and explore why a Philadelphia methadone counsellor stood out – for the wrong reasons.

REVIEW 2012 HTM file
Recovery/remission from substance use disorders: an analysis of reported outcomes in 415 scientific reports, 1868–2011

Positive message of this compendious synthesis of hundreds of studies is that "Recovery is not an aberration achieved by a small and morally enlightened minority of addicted people. If there is a natural developmental momentum within the course of [these] problems, it is toward remission and recovery."

STUDY 2010 HTM file
Problem drug users’ experiences of employment and the benefit system

Substantial barriers to employment were revealed by interviews with problem drug users in England currently or recently in treatment and with staff who worked with drug users. Includes review of relevant international research.

STUDY 2005 PDF file 180Kb
Aftercare calls suit less relapse-prone patients

An intensive US outpatient programme found that for less relapse-prone patients, a flexible aftercare regime mixing initial support groups with regular phone calls was at least as effective as entirely face-to-face contact, yet far less time-consuming.


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