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You have found 112 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with analyses of the most recently published documents, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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REVIEW 2015 HTM file
Prevention of addictive behaviours

Based largely on existing reviews, this report for the German Federal Centre for Health Education comprehensively assesses substance use prevention approaches. Among its many conclusions are that approaches based solely on information provision are ineffective, in contrast to the more positive evidence for lifeskills and multi-component community programmes.

STUDY 2015 HTM file
Impact of opioid substitution therapy for Scotland’s prisoners on drug-related deaths soon after prisoner release

Failure to find effects concentrated in the first two weeks after release persuaded analysts that widespread methadone prescribing in Scottish prisons from 2002 did not reduce the rate of drug-related deaths after release. But over 12 weeks the rate did fall substantially, and methadone treatment may have helped.

STUDY 2015 HTM file
Hepatitis C virus treatment as prevention among injecting drug users: who should we cure first?

In the UK context, this study’s findings imply that to prevent new cases it is best to focus expensive new treatments for hepatitis C infection on injectors who infrequently share their injecting equipment – patients most likely to be found and recruited via needle exchanges and addiction treatment services.

STUDY 2015 HTM file
Opioid treatment at release from jail using extended-release naltrexone: a pilot proof-of-concept randomized effectiveness trial

Though few seemed willing to try this treatment, among those who did, opiate-blocking injections active for about a month helped formerly dependent prisoners in New York City’s jail avoid relapse to regular opiate use after release.

STUDY 2015 HTM file
Impact of treatment for opioid dependence on fatal drug-related poisoning: a national cohort study in England

Implication of this English study is that to save the lives of people dependent on heroin or similar drugs, they should be engaged and retained in substitute prescribing programmes like methadone maintenance until there is little risk of their relapsing after leaving. Shortly after leaving residential/inpatient settings was the highest risk period.

STUDY 2015 HTM file
Adult substance misuse statistics from the National Drug Treatment Monitoring System (NDTMS) 1 April 2014 to 31 March 2015

For the first time the annual accounting of the treatment caseload in England combines both drug and alcohol use patient records, registering a continuing trend down in total numbers due mainly to falls in users of heroin and other opiate-type drugs.

STUDY 2015 HTM file
Changing patterns of substance misuse in adult prisons and service responses

Inspection findings on individual prisons were supplemented by fieldwork in eight prisons in 2014 to generate an overall picture of drug use and responses to it in prisons and England and Wales. In the face of rapidly changing and varied drug use patterns, policy and operational responses were seen as insufficiently flexible and dynamic, though treatment had dramatically improved.

REVIEW 2015 HTM file
Heroin on trial: systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction

The UK has a long history of prescribing heroin for the treatment of heroin dependence. What has research from six countries concluded about this intensive intervention intended for patients who would otherwise be considered ‘unresponsive’ to treatment?

DOCUMENT 2014 HTM file
Needle and syringe programmes

The UK’s health advisory body recommends high coverage and if need be, 24-hour needle exchange to combat HIV and the hepatitis C epidemic. The aim they say is for every injector to have even more sterile injecting equipment than they need for every single injection.

STUDY 2014 HTM file
Rapid decline in HCV incidence among people who inject drugs associated with national scale-up in coverage of a combination of harm reduction interventions

A combination of needle exchange, methadone maintenance and a shift away from injecting meant that between 2008 and 2012, 1000 fewer Scottish injectors had to face chronic infection with the potentially deadly hepatitis C virus.

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