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‘A pill for every ill’ is the gist of the attacks levelled at nalmefene in the form of Selincro, a drug expected to extend the benefits of pharmacotherapy to drinkers not physically dependent or in need of detoxification – or for critics, to medicalise psychosocial dependence on shaky scientific grounds.
DOCUMENT 2016 HTM file
Guidelines on the management of co-occurring alcohol and other drug and mental health conditions in alcohol and other drug treatment settings
Updated guidelines funded by the Australian government recommend universal mental health screening for people accessing substance use services, and say that mental health issues do not pose an “insurmountable barrier” to effective substance use treatment.
REVIEW 2015 HTM file
The efficacy of acamprosate and naltrexone in the treatment of alcohol dependence, Europe versus the rest of the world: a meta-analysis
Whether differences between the patients mean impacts of the alcohol treatment medications acamprosate and naltrexone vary between Europe and the USA was the issue which motivated this fresh analysis of randomised trials. It confirmed the medications’ efficacy and found no evidence that this differed in European trials versus those conducted elsewhere.
REVIEW 2011 HTM file
The efficacy of disulfiram for the treatment of alcohol use disorder
Given effective supervision from family or clinicians to help ensure patients keep taking the tablets, this first systematic synthesis of research finds that on average the drug disulfiram, which produces an unpleasant physical reaction to drinking, does act as an aid to abstinence in the treatment of alcohol dependence.
REVIEW 2012 HTM file
Screening, brief intervention, and referral for alcohol use in adolescents: a systematic review
‘Inconclusive’ was the verdict of a review which aimed to assess the effectiveness of brief alcohol interventions among patients aged 11 to 21 attending for emergency care in the USA. Most promising targets seem to have been the more heavy or irresponsibly drinking among patients who were young adults rather than adolescents.
STUDY 2016 HTM file
Screening for underage drinking and Diagnostic and Statistical Manual of Mental Disorders, 5th Edition alcohol use disorder in rural primary care practice
A US study of young people in rural primary care settings finds that alcohol use disorders can be identified with a single question about frequency of drinking.
STUDY 2016 HTM file
Monitoring and evaluating Scotland’s alcohol strategy: Final
annual report
The final report evaluating Scotland’s alcohol strategy concludes that while some evidence-based interventions have been implemented, failure to implement minimum unit pricing is likely to have limited the strategy’s contribution to declines in both alcohol consumption and related harm.
REVIEW 2008 HTM file
Meta-analysis: Are 3 questions enough to detect unhealthy alcohol use?
Both AUDIT and AUDIT-C are known to accurately detect unhealthy drinking, but is one more accurate than the other? This paper looks for answers in 14 studies from across Europe and in the United States.
A major study conducted in London did not find clinically important reductions in drinking among excessive drinkers offered a brief intervention while attending sexual health clinics, nor did brief intervention seem a cost-effective use of health service resources.
REVIEW 2013 HTM file
Interventions for reducing alcohol consumption among general hospital inpatient heavy alcohol users: a systematic review
Review of studies of interventions for heavy drinkers identified among general hospital inpatients concluded that multi-session brief interventions could reduce drinking. “Could” is an important qualifier: yet to be pinned down is why though sometimes they work, brief interventions often fail to produce significant effects.
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