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You have found 119 entries after clicking the GO button or a search link in a hot topic. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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HOT TOPIC 2017 HTM file
Overdose antidote naloxone takes harm-reduction centre stage

‘Hot topics’ offer background and analysis on important issues which sometimes generate heated debate. National programmes distributing the opiate overdose antidote naloxone have become the great hope for curbing the rise in overdose deaths, but England is lagging behind the rest of the UK – and planning for the likelihood not of recovery but relapse may for some services and patients be hard to accept.

STUDY 2016 HTM file
Effectiveness of Scotland’s National Naloxone Programme for reducing opioid-related deaths: a before (2006–10) versus after (2011–13) comparison

In 2011 Scotland became the first country to fund a national policy of distributing the opiate-blocker naloxone to prevent deaths involving opiate-type drugs. According to this evaluation it did prevent deaths where the effect was most likely to be seen – in the weeks after release from prison.

REVIEW 2014 HTM file
Estimating the efficacy of Alcoholics Anonymous without self-selection bias: an instrumental variables re-analysis of randomized clinical trials

12-step fellowships offer a way to reconcile shrunken resources with the desire to get more patients safely out of treatment. Accounting for the self-selection bias which has obscured AA’s impacts, this synthesis of US trials finds that attending more meetings after treatment boosts abstinence. Why then is research equivocal on whether promoting attendance improves drink-related outcomes?

STUDY 2013 HTM file
Cost-effectiveness of distributing naloxone to heroin users for lay overdose reversal

The first simulation of the cost-effectiveness of supplying naloxone kits to heroin users to enable them to prevent overdose deaths estimates that in the US context these programmes would be well within the range considered a cost-effective health intervention. Findings are likely to broadly apply to the UK, one weak link being whether drug users given the kits actually carry them around.

DOCUMENT 2016 HTM file
Coexisting severe mental illness and substance misuse: community health and social care services

NICE guidance on health and social care for substance users with severe mental illness says that rather than creating specialist ‘dual diagnosis’ services, health and social care (including substance misuse) services should adapt to this caseload, and their care should be led by the mental health service.

DOCUMENT 2012 HTM file
Quality standard for drug use disorders

Official UK quality standards on the treatment of adults for problems related to the use of illegal drugs, intended be used to plan and deliver services to provide the best possible care.

STUDY 2015 HTM file
Navigating the alcohol treatment pathway: A qualitative study from the service users’ perspective

Patient interviews provide insight into low levels of engagement and retention in alcohol treatment services, hindering the effective provision of treatment for dependent drinkers. Findings suggest that treatment pathways should better reflect the capacity and capabilities of people with alcohol dependence.

STUDY 2012 HTM file
Drug system change pilots evaluation: final report

Based on the yardstick of successful treatment completions, government-funded research in England offers no assurance that recovery-oriented redesigns of local treatment systems have generated more or more rapid recovery from addiction than usual arrangements. Evidence was stronger for focused attempts to improve continuity of care for offenders.

REVIEW 2016 HTM file
Patient preferences and shared decision-making in the treatment of substance use disorders: a systematic review of the literature

The first review to evaluate shared decision-making and patient preferences for substance use treatment finds evidence that greater patient involvement in decisions can improve outcomes and has no negative impacts.

REVIEW 2015 HTM file
Risks and benefits of nalmefene in the treatment of adult alcohol dependence: a systematic literature review and meta-analysis of published and unpublished double-blind randomized controlled trials

‘A pill for every ill’ is the gist of the attacks levelled at nalmefene in the form of Selincro, a drug expected to extend the benefits of pharmacotherapy to drinkers not physically dependent or in need of detoxification – or for critics, to medicalise psychosocial dependence on shaky scientific grounds.


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