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REVIEW 2010 HTM file
Optimal provision of needle and syringe programmes for injecting drug users: a systematic review
This thorough review formed the evidential basis for recent guidance from England's National Institute for Health and Clinical Excellence on how best to distribute sterile syringes. Maximising the proportion of injections done with sterile equipment is the key objective.
STUDY 2005 PDF file 115Kb
Simple interventions cut hepatitis C risk
In Australia a detailed assessment of an injector's risk of becoming infected with hepatitis C was followed by substantial risk reductions not improved on by individualised advice.
STUDY 2012 HTM file
Can needle and syringe programmes and opiate substitution therapy achieve substantial reductions in hepatitis C virus prevalence?
Among the messages of this simulation model for the UK and other countries is the resilience of hepatitis C in the face of considerable investment in methadone and needle exchange services, that these have nevertheless helped and need to be maintained and if possible expanded, but also that further measures are required to substantially curtail the virus.
National survey of injectors attending services supplying injecting equipment suggests methadone maintenance plus an abundant supply of needles and syringes help protect Scottish injectors from infection by hepatitis C.
STUDY 2019 HTM file
Increased diagnosis and treatment of hepatitis C in prison by universal offer of testing and use of telemedicine
How can testing and treatment for hepatitis C be optimised in custodial settings? Prisons in the North East of England trialled new care pathways including a universal offer of testing using less invasive procedures and treatment facilitated by digital technology.
STUDY 2010 HTM file
Reducing sex under the influence of drugs or alcohol for patients in substance abuse treatment
At issue was whether among men in treatment for substance use problems the standard one session of HIV education could be improved on by five sessions including motivational exercises and skills training. In the short term there were greater reductions in sex under the influence but these did not last.
STUDY 2010 HTM file
Brief counseling for reducing sexual risk and bacterial STIs among drug users. Results from project RESPECT
Across this large US study, injectors responded to sexual risk-reduction counselling as well as non-injectors; the evidence was there a year later in fewer infections. But why was what should have been the strongest intervention actually the weakest among this group, yet not among non-injectors?
SERIES OF ARTICLES 2001 PDF file 3944Kb
Overdosing on opiates
The most thorough review to date of the greatest risk posed by illegal drug use in Britain. An international team of authors analyses the causes and how to prevent opiate overdose deaths.
REVIEW 2000 PDF file 2709Kb
Overdosing on opiates part I: causes
The most thorough review to date of the greatest risk posed by illegal drug use in Britain. An international team of authors analyses the causes and finds they go way beyond just taking too much. Includes in the “The Swedish experience” on p. 6 of PDF early studies which established methadone’s lifesaving potential.
STUDY 2015 HTM file
Impact of treatment for opioid dependence on fatal drug-related poisoning: a national cohort study in England
Implication of this English study is that to save the lives of people dependent on heroin or similar drugs, they should be engaged and retained in substitute prescribing programmes like methadone maintenance until there is little risk of their relapsing after leaving. Shortly after leaving residential/inpatient settings was the highest risk period.
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