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STUDY 1999 PDF file 255Kb
Methadone treatment cost-effective life saver
Three studies which show that getting in to and staying in methadone treatment cost-effectively saves the lives of heroin addicts. Conversely, being denied treatment or discharged for rule-breaking costs lives.
STUDY 2000 PDF file 111Kb
Careful induction prevents overdose deaths among methadone patients
Studies from Australia and Scotland both find that overdose death during methadone maintenance is closely related to continued illegal drug use in the early stages of treatment.
STUDY 2001 PDF file 161Kb
Under-dosing and poor initial assessment undermine success of British methadone services
Reports from the NTORS study in England confirm that the benefits of methadone prescribing persist to two years after treatment entry though nearly a fifth of patients do not respond well to an often ill-defined programme not delivered as intended.
STUDY 2002 PDF file 183Kb
No harm and some benefit in letting methadone patients choose their dose
US study shows that methadone maintenance patients allowed to set their own doses do not escalate excessively. Benefits may include improved patient-therapist relations and reduced illicit drug use. Extended text reviews other relevant studies.
STUDY 2004 PDF file 159Kb
Methadone maintenance as low-cost lifesaver
US studies find that even when slow methadone detoxification is bolstered by psychosocial therapy and aftercare, methadone maintenance does better at prolonging the lives of opiate-dependent patients at relatively little extra cost.
IN PRACTICE 2005 PDF file 927Kb
Barriers cleared in Endell Street
How a team in London's West End set about systematically overcoming the barriers which prevented the residents of a homelessness hostel getting the treatment they needed. The key step was simple – asking the residents just what it was which stood in the way.
STUDY 2008 HTM file
Mortality prior to, during, and after opioid maintenance treatment (OMT): a national prospective cross-registry study
Limited access to opiate substitute prescribing in Norway opened a window on its powerful lifesaving potential, a view obscured in countries where barriers create a confounding selection effect or where everyone who needs and wants this treatment can quickly get it.
STUDY 2006 PDF file 207Kb
Methadone maintenance: the original
In the mid-60s even its originators doubted whether methadone maintenance could work when everything else had failed, gnawing their nails as they waited for patients to return from the temptations outside the ward. What they saw instead was a 'miraculous' transformation.
REVIEW 2009 HTM file
Pharmacotherapies for the treatment of opioid dependence: efficacy, cost-effectiveness and implementation guidelines
From some of the same Australian authors who produced classic texts on maintenance prescribing for heroin addiction, a major new text analysing research on all types of drug-based interventions including maintenance, opiate-blocking drugs, and managing withdrawal.
STUDY 2006 PDF file 145Kb
Stripped down methadone prescribing better than leaving patients to wait
What can you do if patients have to wait for a methadone slot? This US study found that offering a bare-bones substitute prescribing service during the waiting period meant patients felt better, used drugs less and were more likely eventually to enter the fully-fledged programme.
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