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You have found 446 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Starting with analyses of the most recently published documents, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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STUDY 2015 HTM file
Adult substance misuse statistics from the National Drug Treatment Monitoring System (NDTMS) 1 April 2014 to 31 March 2015

For the first time the annual accounting of the treatment caseload in England combines both drug and alcohol use patient records, registering a continuing trend down in total numbers due mainly to falls in users of heroin and other opiate-type drugs.

STUDY 2015 HTM file
Fatal opioid poisoning: a counterfactual model to estimate the preventive effect of treatment for opioid use disorder in England

First robust analysis estimates that between 2008 and 2011, 880 opioid-related ‘overdose’ deaths were prevented each year by addiction treatment in England, reducing total deaths by over 40%.

STUDY 2015 HTM file
Using behavioral triage in court-supervised treatment of DUI offenders

From California, the first evaluation of a system which escalated drink/drug drivers to treatment if they failed a less intensive sentence found significantly reduced recidivism and accidents, and evidence that injuries related to accidents also fell.

STUDY 2015 HTM file
Changing patterns of substance misuse in adult prisons and service responses

Inspection findings on individual prisons were supplemented by fieldwork in eight prisons in 2014 to generate an overall picture of drug use and responses to it in prisons and England and Wales. In the face of rapidly changing and varied drug use patterns, policy and operational responses were seen as insufficiently flexible and dynamic, though treatment had dramatically improved.

STUDY 2015 HTM file
A double blind, placebo controlled trial of modafinil for the treatment of cocaine dependence without co-morbid alcohol dependence

Modafinil is a mild stimulant which it is hoped might plug the gap in effective pharmacotherapies for dependence on cocaine. Though this trial found that it promoted abstinence from cocaine, others have not, and its inconsistent benefits have been seen as failing to outweigh the drug’s side effects.

HOT TOPIC 2015 HTM file
Prescribing opiate-type drugs to opiate addicts: good sense or nonsense?

One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. For decades deeply felt and at times intemperate debate has surrounded a treatment which achieves unparalleled success by going with the grain of addiction, prescribing the same type of drug which opiate-dependent patients used illegally – a substitution castigated as surrender or hailed as an enlightened lifesaver.

STUDY 2015 HTM file
Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial

Unique trial tests what emergency doctors should do when screening identifies opioid dependence. More effective at promoting treatment and curbing opioid use than referral and brief advice was, it seems, actually initiating treatment in the form of buprenorphine maintenance.

REVIEW 2015 HTM file
The effectiveness and cost-effectiveness of diversion and aftercare programmes for offenders using class A drugs: a systematic review and economic evaluation

Although diversionary schemes continue to be a strategic focus for policy in relation to tackling drug-related problems, UK review finds that the evidence base for the effectiveness of these schemes is lacking.

REVIEW 2015 HTM file
Heroin on trial: systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction

The UK has a long history of prescribing heroin for the treatment of heroin dependence. What has research from six countries concluded about this intensive intervention intended for patients who would otherwise be considered ‘unresponsive’ to treatment?

DOCUMENT 2014 HTM file
Needle and syringe programmes

The UK’s health advisory body recommends high coverage and if need be, 24-hour needle exchange to combat HIV and the hepatitis C epidemic. The aim they say is for every injector to have even more sterile injecting equipment than they need for every single injection.

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