Matrix search results
You have found 363 entries after clicking on a search link (usually the MORE information link) in a matrix cell. Sorted by the main topic addressed, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.
Click blue titles to view full text in a new window Use the selectors at the bottom to turn to the next page in the list of documents Re-order the list by the most recently added or updated entries or by the most recently published documents
If you have not found what you want you could: Select from the full range of topics and search options available on our topic search page.
Instead try a free text search for documents which contain the words you specify.
Or try browsing back issues of the magazine or the more recent email bulletins.
Try the information services provided by partner agencies.
Tried everything? E-mail the Findings editor for help by clicking on this logo 
REVIEW 2011 HTM file
The efficacy of disulfiram for the treatment of alcohol use disorder
Given effective supervision from family or clinicians to help ensure patients keep taking the tablets, this first systematic synthesis of research finds that on average the drug disulfiram, which produces an unpleasant physical reaction to drinking, does act as an aid to abstinence in the treatment of alcohol dependence.
STUDY 1992 HTM file
Disulfiram treatment of alcoholism
Still relevant today, from the early 1990s a UK randomised trial of disulfiram in the treatment of alcohol dependence found that it significantly reduced drinking when there was daily supervision to make sure patients took the tablets, and they knew these would cause unpleasant physical effects if they drank.
STUDY 2002 PDF file 199Kb
A way to encourage drinkers to stick with naltrexone treatment
An intervention which helps overcome the major impediments to naltrexone treatment of alcoholism – patients don't take the pills or drop out – has now been codified in a book which acts as a manual for conducting the intervention.
STUDY 2005 PDF file 142Kb
Anti-alcohol drug also reduces cocaine use
US trial shows that when cocaine dependence and heavy drinking are intertwined, prescribing the anti-alcohol medication disulfiram helps resolve both problems, unless patients are so wedded to drink that they stop taking the pills.
STUDY 2005 PDF file 170Kb
'Real-world' studies show that medications do suppress heavy drinking
Three trials found that drugs commonly used to treat alcohol dependence improve outcomes for an appreciable minority of patients, even under conditions close to normal practice. Together they offer clues to who benefits most from each medication.
REVIEW 2009 HTM file
The state of pharmacotherapy for the treatment of alcohol dependence
Review finds some but inconsistent and often modest support for each of the four medications approved by the US administration for the treatment of alcohol dependence: disulfiram; acamprosate; oral naltrexone; and once-monthly, injectable, extended-release naltrexone.
STUDY 2006 PDF file 170Kb
Naltrexone aids primary care alcohol treatment
Findings from the large-scale US COMBINE study add to accumulating evidence that the drug naltrexone is a valuable therapeutic enhancement for the kind of dependent drinkers and the kind of treatments suited to primary care settings.
REVIEW 2011 HTM file
Medical treatment of alcohol dependence: a systematic review
With from 2011 naltrexone licensed for this purpose, Britain now has the full suite of major medications authorised for the treatment of alcohol dependence. Largely from a primary care perspective, this US review examines a half century of evidence for whether these and other drugs aid recovery and which work best.
REVIEW 2012 HTM file
Acamprosate for alcohol dependence: a sex-specific meta-analysis based on individual patient data
The first comprehensive analysis of whether acamprosate treatment works as well for alcohol-dependent women as for men definitively concludes that across 22 mainly European trials it has had a virtually identical impact. The analysis also reports the drug's overall impact, finding that it helps prevent heavy drinking as well as fostering abstinence.
STUDY 2010 HTM file
Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study
Reanalysis of the largest US study of medication-based alcoholism treatment confirms that either naltrexone or psychological therapy improved outcomes more than medical care and placebos, while the two in combination or acamprosate added little. It also revealed previously invisible benefits when certain types of patients received certain treatments.
Select search results page
PREVIOUS
|
NEXT
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37